| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LRRFIP1 |
| Specificity: |
This antibody reacts specifically with LRRFIP1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LRRFIP1 |
| Gene ID: |
9208 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Flightless I has a C-terminal TaR-like domain which binds Actin and therefore the association of LRRFIP1 with the LRR of Flightless I may provide a link between the Actin cytoskeleton and RNA in mammalian cells, In contrast, LRRFIP1 binds double-stranded RNA with high affinity, LRRFIP1 does not bind single-stranded DNA or RNA significantly and binds double-stranded DNA weakly, LRRFIP1 is also believed to control smooth muscle cell proliferation following arterial injury through PDGF-A repression, The N-terminus of LRRFIP1 shows high homology to the coiled-coil domain of FLAP, The RNA binding domain has been identified and encompasses a lysine-rich motif, a protein which binds the leucine-rich repeat (LRR) of Flightless I, and the interaction of LRRFIP1 with the LRR of Flightless I has been confirmed, and two molecules of LRRFIP1 bind the TaR stem, LRRFIP1 is an 738 amino acid human protein whose rodent counterpart is known as Lrrfip1 (also designated FLAP in mouse) |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
FLAP-1 FLIIAP1 TRIP GCF-2 HUFI-1 |
| Also known as: |
LRRFIP1 Polyclonal Antibody |
| Other name: |
Anti-LRRFIP1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
LRRFIP1 |
| Short name: |
Anti-LRRFIP1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-LRRFIP1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6702 |
| Gene: |
LRRFIP1 |
More about : LRRFIP1 |
| Long gene name: |
LRR binding FLII interacting protein 1 |
| Synonyms gene name: |
leucine rich repeat (in FLII) interacting protein 1 |
| Synonyms name: |
GC-binding factor 2 |
| Locus: |
2q37, 3 |
| Discovery year: |
1999-02-15 |
| GenBank acession: |
AJ223075 |
| Entrez gene record: |
9208 |
| Pubmed identfication: |
9705290 9525888 16199883 |
| RefSeq identity: |
NM_004735 |
| Havana BLAST/BLAT: |
OTTHUMG00000133339 |