| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
TLR5 |
| Specificity: |
This antibody reacts specifically with TLR5 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse TLR5 |
| Gene ID: |
53791 |
| Swiss Prot: |
Q9JLF7 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Acts via MYD88 and TRAF6, Mediates detection of bacterial flagellins, cytokine secretion and the inflammatory response (By similarity), leading to NF-kappa-B activation, Participates in the innate immune response to microbial agents |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
TIL3 FLJ10052 MGC126430 MGC126431 |
| Also known as: |
TLR5 Polyclonal Antibody |
| Other name: |
Anti-TLR5 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
TLR5 |
| Short name: |
Anti-TLR5 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-toll-like receptor 5 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
MELIOS and SLE1 and SLEB1 and TIL3, Plasma membranes, TLR5 and IDBG-106840 and ENSG00000187554 and 7100, TLR5 and IDBG-648348 and ENSBTAG00000000477 and 444870, Tlr5 and IDBG-259066 and ENSMUSG00000079164 and 53791, protein binding, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0008584 and male this GO nad development and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005149 : interleukin-1 receptor binding and also this GO :0005515 : protein binding, this GO :0005149 : interleukin-1 receptor binding, this GO :0005515 : protein binding, toll-like receptor 5 |
| Identity: |
11851 |
| Gene: |
TLR5 |
More about : TLR5 |
| Long gene name: |
toll like receptor 5 |
| Synonyms gene: |
SLEB1 |
| Synonyms gene name: |
systemic lupus erythematosus susceptibility 1 toll-like receptor 5 |
| Synonyms name: |
Toll/interleukin-1 receptor-like protein 3 |
| Locus: |
1q41 |
| Discovery year: |
1998-06-25 |
| Entrez gene record: |
7100 |
| Pubmed identfication: |
9435236 16027372 |
| RefSeq identity: |
NM_003268 |
| Classification: |
Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000037937 |