| known also as: |
Anti-RABBIT ANTI HUMAN TLR5 |
| known also as: |
RABBIT ANTI HUMAN TLR5 |
| known also as: |
Lapin ANTI Homo sapiens TLR5 |
| known also as: |
TLR5 |
| Other names: |
Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, toll-like receptor 5, toll-like receptor 5, toll/interleukin-1 receptor-like protein 3, toll-like receptor 5 |
| Gene name: |
TLR5 |
| Other gene names: |
SLEB1, TIL3, TIL3, TLR5, TLR5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
TLR5 acts via a cytokine signaling pathway to induce the activation of NF-kappaB and in turn tumour necrosis factor alpha and has been shown to recognise flagellin from both Gram-positive and Gram-negative bacteria, _x000D_, _x000D__x000D_TLRs play an important role in the recognition of invading microbial pathogens during innate immunity, a 97, acting through adaptor molecules such as MyD88 and TRAF6, expressed at high levels in the liver and detectable in small amounts in most other tissues, 6kDa member of the evolutionarily conserved toll-like receptor family (TLRs), TLR5 This item recognises human Toll-like receptor 5 (TLR5) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Western Blot (WB), Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
TLR5 |
| Short name: |
Anti-HUMAN TLR5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens toll-like receptor 5 (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
MELIOS and SLE1 and SLEB1 and TIL3, Plasma membranes, TLR5 and IDBG-106840 and ENSG00000187554 and 7100, TLR5 and IDBG-648348 and ENSBTAG00000000477 and 444870, Tlr5 and IDBG-259066 and ENSMUSG00000079164 and 53791, protein binding, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0008584 and male this GO nad development and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005149 : interleukin-1 receptor binding and also this GO :0005515 : protein binding, this GO :0005149 : interleukin-1 receptor binding, this GO :0005515 : protein binding, toll-like receptor 5 |
| Identity: |
11851 |
| Gene: |
TLR5 |
More about : TLR5 |
| Long gene name: |
toll like receptor 5 |
| Synonyms gene: |
SLEB1 |
| Synonyms gene name: |
systemic lupus erythematosus susceptibility 1 toll-like receptor 5 |
| Synonyms: |
TIL3 FLJ10052 MGC126430 MGC126431 |
| Synonyms name: |
Toll/interleukin-1 receptor-like protein 3 |
| Locus: |
1q41 |
| Discovery year: |
1998-06-25 |
| Entrez gene record: |
7100 |
| Pubmed identfication: |
9435236 16027372 |
| RefSeq identity: |
NM_003268 |
| Classification: |
Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000037937 |