Anti-SPR/Sepiapterin reductase, ALEXA Fluor 594

Catalog number:	GENTAUR-58be5bb4e8ceb Buy Now
Price:	2282 €
Supplier:	MBS Recombinant Proteins
Product name:	Anti-SPR/Sepiapterin reductase, ALEXA Fluor 594
Quantity:	100ug
Related search:	reductase antibody spr sepiapterin gene species short synonyms

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Type:	Conjugated Primary Antibody
Conjugated with:	594, ALEXA FLUOR®
Host organism:	Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide:	SPR/Sepiapterin reductase
Specificity:	This antibody reacts specifically with SPR/Sepiapterin reductase
Modification:	No modification has been applied to this antibody
Modification site:	None
Clonality:	Polyclonal Antibody
Clone:	Polyclonal Antibodies
Concentration:	1ug per 1ul
Antigen Source:	KLH conjugated synthetic peptide derived from human Sepiapterin reductase
Applications:	IF(IHC-P)
Applications with corresponding dilutions:	IF(IHC-P)(1:50-200)
Cross reactive species:	Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens)
Cross Reactive Species details:	However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species
Background information:	BH4 is an essential cofactor for the hydroxylation of the aromatic amino acids (tryptophan, In addition, In addition, Mutations in the gene encoding SPR can cause sepiapterin reductase deficiency, SPR functions as an NADH-dependent aldo-keto reductase and specifically catalyzes the reduction of pteridine derivatives, SPR mRNA expression is increased in the brain of Parkinsonâ, SPR plays an important role in tetrahydrobiopterin (BH4) biosynthesis, Sepiapterin reductase deficiency interferes with BH4 synthesis, a monoamine neurotransmitter deficiency without hyperphenylalaninemia, also known as sepiapterin reductase, catalyzing the final reduction step of the synthesis pathway, is a homodimeric cytoplasmic protein that belongs to the sepiapterin reductase family, resulting in DOPA-responsive dystonia and a variety of other human diseases, suggesting that SPR may play a role in PD, tyrosine and phenylalanine) and is required for proper dopamine synthesis, &euro, &trade, SPR, s Disease (PD) patients
Purification method:	Purified by Protein A
Storage:	50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA
Excitation emission:	590nm/617nm
Synonyms:	SDR38C1
Also known as:	SPR/Sepiapterin reductase Antibody
Other name:	Anti-SPR/Sepiapterin reductase
Advisory:	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody
Properties:	For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	SPR/Sepiapterin reductase
Short name:	Fluor 594, Anti-SPR/Sepiapterin reductase
Label:	ALEXA
Alternative name:	ALEXA Fluor 594, antibody to-SPR/Sepiapterin reductase
Identity:	11257
Gene:	SPR | More about : SPR
Long gene name:	sepiapterin reductase (7, 8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms name:	member 1 , short chain dehydrogenase/reductase family 38C
Locus:	2p13, 2
Discovery year:	1991-12-05
Entrez gene record:	6697
Pubmed identfication:	1883349 19027726
Classification:	Short chain dehydrogenase/reductase superfamily
Havana BLAST/BLAT:	OTTHUMG00000129777
Locus Specific Databases:	BIOMBD

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