| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
GCH1 |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB |
| Recommended dilutions: |
5-2ug/ml, ELISA (peptide) LOD: 1:16000, Western blot: 0 |
| Notes: |
Optimal dilution of the GCH1 antibody should be determined by the researcher |
| Intented use: |
This GCH1 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
2643 |
| Purity: |
Antigen affinity |
| Description: |
Additional name(s) for this target protein: GTP cyclohydrolase 1 |
| Immunogen: |
Amino acids GKVHIGYLPNKQ were used as the immunogen for this GCH1 antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the GCH1 antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
GCH1 |
| Short name: |
GCH1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GTP cyclohydrolase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DYT14 and DYT5 and DYT5a and GCH and GTP-CH-1 and GTPCH1 and HPABH4B, GCH1 and IDBG-646712 and ENSBTAG00000040151 and 286815, GCH1 and IDBG-7150 and ENSG00000131979 and 2643, Gch1 and IDBG-154178 and ENSMUSG00000037580 and 14528, coenzyme binding, nuclei, this GO :0003934 and GTP cyclohydrolase I activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006729 and tetrahydrobiopterin biosynthetic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0008152 and metabolic process and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0014916 and regulation of lung blood pressure and biological process this GO :0030742 and GTP-dependent protein binding and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034341 and response to interferon-gamma and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035998 and 7, this GO :0003934 : GTP cyclohydrolase I activity, this GO :0003934 : GTP cyclohydrolase I activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding and also this GO :0008270 : zinc ion binding and also this GO :0030742 : GTP-dependent protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0050662 : coenzyme binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, this GO :0008270 : zinc ion binding, this GO :0030742 : GTP-dependent protein binding, this GO :0042803 : protein homodimerization activity, this GO :0050662 : coenzyme binding, 8-dihydroneopterin 3'-triphosphate biosynthetic process and biological process this GO :0042311 and vasodilation and biological process this GO :0042416 and dopamine biosynthetic process and biological process this GO :0042559 and pteridine-containing compound biosynthetic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0045776 and negative regulation of blood pressure and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0046654 and tetrahydrofolate biosynthetic process and biological process this GO :0048265 and response to pain and biological process this GO :0050662 and coenzyme binding and molecular function this GO :0050884 and neuromuscular process controlling posture and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051066 and dihydrobiopterin metabolic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process, GTP cyclohydrolase 1 |
| Identity: |
4193 |
| Gene: |
GCH1 |
More about : GCH1 |
| Long gene name: |
GTP cyclohydrolase 1 |
| Synonyms gene: |
GCH DYT5 DYT14 |
| Synonyms gene name: |
dystonia 14 |
| Synonyms: |
GTPCH1 DYT5a |
| Synonyms name: |
dopa-responsive dystonia |
| Locus: |
14q22, 2 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
U19523 |
| Entrez gene record: |
2643 |
| Pubmed identfication: |
7874165 8695054 |
| Havana BLAST/BLAT: |
OTTHUMG00000029754 |
| Locus Specific Databases: |
BIOMDBdb: Database of Mutations Causing BH4 Deficiencies and other PND |