| known also as: |
Anti-Goat anti-GCH1 Antibody |
| known also as: |
Anti-, Caprine anti-GCH1 |
| known also as: |
Caprinae anti-GCH1 Antibody |
| known also as: |
GCH1 |
| known also as: |
DYT5, DYT5, GCH, GCH, GCH1, GTP cyclohydrolase 1, GTP cyclohydrolase 1, GTP cyclohydrolase 1 (dopa-responsive dystonia), GTP cyclohydrolase 1 (dopa-responsive dystonia), GTP-CH-1, GTP-CH-1, GTPCH1, GTPCH1, guanosine 5'-triphosphate cyclohydrolase I, guanosine 5\1-triphosphate cyclohydrolase I, GCH1 |
| Other names: |
GTP cyclohydrolase 1, GTP cyclohydrolase 1, GTP cyclohydrolase 1, GTP cyclohydrolase I, GTP cyclohydrolase I, GTP-CH-I, GTP-CH-I, dystonia 14, guanosine 5'-triphosphate cyclohydrolase I, GTP cyclohydrolase 1 isoform 1 |
| Gene name: |
GCH1 |
| Other gene names: |
DYT14, DYT5, DYT5, DYT5a, GCH, GCH, GCH1, GTP-CH-1, GTP-CH-I, GTPCH1, HPABH4B, GCH1 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Mouse, Rat, Human |
| Purification method: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide |
| Form/Appearance: |
0, pH7, 02% sodium azide, 3 with 0, 5 mg/ml in Tris saline, 5% bovine serum albumin, Supplied at 0, _x000D_ |
| Concentration: |
100ug specific antibody in 200ul |
| Storage and shipping: |
Cycles of freezing and thawing should be avoided as they may damage the polypeptide chains thus reducing the activity of the antibody, After been aliquoted the antibody should be stored at -20 degrees Celsius |
| Tested for:: |
Western Blot (WB), Peptide ELISA (EIA) |
| Description: |
Freeze thaw will destroy a percentage in every cycle and should be avoided, C in a fridge short term in a concentrated dilution, This antibody needs to be stored at + 4° |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Latin name: |
Capra aegagrus hircus |
| Gene target: |
GCH1 |
| Short name: |
Goat anti-GCH1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody to, goats, Antibody |
| Host: |
It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species: |
Goats |
| Alternative name: |
caprine antibody to-GTP cyclohydrolase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DYT14 and DYT5 and DYT5a and GCH and GTP-CH-1 and GTPCH1 and HPABH4B, GCH1 and IDBG-646712 and ENSBTAG00000040151 and 286815, GCH1 and IDBG-7150 and ENSG00000131979 and 2643, Gch1 and IDBG-154178 and ENSMUSG00000037580 and 14528, coenzyme binding, nuclei, this GO :0003934 and GTP cyclohydrolase I activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0006461 and protein complex assembly and biological process this GO :0006729 and tetrahydrobiopterin biosynthetic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0008152 and metabolic process and biological process this GO :0008217 and regulation of blood pressure and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0014916 and regulation of lung blood pressure and biological process this GO :0030742 and GTP-dependent protein binding and molecular function this GO :0031410 and cytoplasmic vesicle and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0034341 and response to interferon-gamma and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035998 and 7, this GO :0003934 : GTP cyclohydrolase I activity, this GO :0003934 : GTP cyclohydrolase I activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0005525 : GTP binding and also this GO :0008270 : zinc ion binding and also this GO :0030742 : GTP-dependent protein binding and also this GO :0042803 : protein homodimerization activity and also this GO :0050662 : coenzyme binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0005525 : GTP binding, this GO :0008270 : zinc ion binding, this GO :0030742 : GTP-dependent protein binding, this GO :0042803 : protein homodimerization activity, this GO :0050662 : coenzyme binding, 8-dihydroneopterin 3'-triphosphate biosynthetic process and biological process this GO :0042311 and vasodilation and biological process this GO :0042416 and dopamine biosynthetic process and biological process this GO :0042559 and pteridine-containing compound biosynthetic process and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043234 and protein complex and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0045776 and negative regulation of blood pressure and biological process this GO :0046209 and nitric oxide metabolic process and biological process this GO :0046654 and tetrahydrofolate biosynthetic process and biological process this GO :0048265 and response to pain and biological process this GO :0050662 and coenzyme binding and molecular function this GO :0050884 and neuromuscular process controlling posture and biological process this GO :0050999 and regulation of nitric-oxide synthase activity and biological process this GO :0051000 and positive regulation of nitric-oxide synthase activity and biological process this GO :0051066 and dihydrobiopterin metabolic process and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051291 and protein heterooli this GO merization and biological process, GTP cyclohydrolase 1 |
| Identity: |
4193 |
| Gene: |
GCH1 |
More about : GCH1 |
| Long gene name: |
GTP cyclohydrolase 1 |
| Synonyms gene: |
GCH DYT5 DYT14 |
| Synonyms gene name: |
dystonia 14 |
| Synonyms: |
GTPCH1 DYT5a |
| Synonyms name: |
dopa-responsive dystonia |
| Locus: |
14q22, 2 |
| Discovery year: |
1988-05-11 |
| GenBank acession: |
U19523 |
| Entrez gene record: |
2643 |
| Pubmed identfication: |
7874165 8695054 |
| Havana BLAST/BLAT: |
OTTHUMG00000029754 |
| Locus Specific Databases: |
BIOMDBdb: Database of Mutations Causing BH4 Deficiencies and other PND |