| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAI3 |
| Specificity: |
This antibody reacts specifically with RAI3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RAI3 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
RAI3 expression is upregulated in most tumor cell lines that express mutant p53, RAI3 is a potential molecular target for diagnosing breast cancer, RAI3 may also be involved in maintaining homeostasis of epithelial cells, Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation, and apoptosis, and selective suppression of signals from RAI3 may have a place in breast cancer treatments, cell growth, differentiation, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis, RAI3 is an transmembrane G-protein-coupled receptor that affects many essential biological processes including embryogenesis |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RAIG1 TIG1 PEIG-1 |
| Also known as: |
RAI3 Polyclonal Antibody |
| Other name: |
Anti-RAI3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAI3 |
| Short name: |
Anti-RAI3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RAI3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9836 |
| Gene: |
GPRC5A |
More about : GPRC5A |
| Long gene name: |
G protein-coupled receptor class C group 5 member A |
| Synonyms gene: |
RAI3 |
| Synonyms gene name: |
class C, group 5, member A , retinoic acid induced 3 G protein-coupled receptor |
| Locus: |
12p13, 1 |
| Discovery year: |
1999-01-12 |
| GenBank acession: |
AF095448 |
| Entrez gene record: |
9052 |
| Pubmed identfication: |
8832110 9857033 |
| RefSeq identity: |
NM_003979 |
| Classification: |
Class C orphans , G protein-coupled receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000168710 |