| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
DUOX2 |
| Specificity: |
This antibody reacts specifically with DUOX2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human DUOX2 |
| Gene ID: |
50506 |
| Swiss Prot: |
Q9NRD8 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
May have its own peroxidase activity through its N-terminal peroxidase-like domain, Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa, Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
P138-TOX P138(TOX) THOX2 LNOX2 |
| Also known as: |
DUOX2 Polyclonal Antibody |
| Other name: |
Anti-DUOX2 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
DUOX2 |
| Short name: |
Anti-DUOX2 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-dual oxidase 2 (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DUOX2 and IDBG-10041 and ENSG00000140279 and 50506, DUOX2 and IDBG-646700 and ENSBTAG00000016234 and 785698, Duox2 and IDBG-202825 and ENSMUSG00000068452 and 214593, Plasma membranes, heme binding, this GO :0004601 and peroxidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0006590 and thyroid hormone generation and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0009566 and fertilization and biological process this GO :0009615 and response to virus and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016174 and NAD(P)H oxidase activity and molecular function this GO :0016324 and apical plasma membrane and cellular component this GO :0016491 and oxidoreductase activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0020037 and heme binding and molecular function this GO :0030282 and bone mineralization and biological process this GO :0030878 and thyroid gland development and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0042335 and cuticle development and biological process this GO :0042403 and thyroid hormone metabolic process and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0042446 and hormone biosynthetic process and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0048839 and inner ear development and biological process this GO :0048855 and adenohypophysis morphogenesis and biological process this GO :0051591 and response to cAMP and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004601 : peroxidase activity, this GO :0004601 : peroxidase activity and also this GO :0005509 : calcium ion binding and also this GO :0016174 : NAD(P)H oxidase activity and also this GO :0016491 : oxidoreductase activity and also this GO :0020037 : heme binding, this GO :0005509 : calcium ion binding, this GO :0016174 : NAD(P)H oxidase activity, this GO :0016491 : oxidoreductase activity, this GO :0020037 : heme binding, dual oxidase 2 |
| Identity: |
13273 |
| Gene: |
DUOX2 |
More about : DUOX2 |
| Long gene name: |
dual oxidase 2 |
| Synonyms name: |
dual oxidase-like domains 2 nicotinamide adenine dinucleotide phosphate oxidase flavoprotein NADPH oxidase NADPH thyroid oxidase 2 NADH/NADPH thyroid oxidase p138-tox NADPH oxidase/peroxidase DUOX2 |
| Locus: |
15q21, 1 |
| Discovery year: |
2000-11-09 |
| GenBank acession: |
AF181972 |
| Entrez gene record: |
50506 |
| Pubmed identfication: |
10601291 10806195 |
| RefSeq identity: |
NM_014080 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131355 |