| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Laminin alpha 4 |
| Specificity: |
This antibody reacts specifically with Laminin alpha 4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse Laminin alpha 4 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Rat (Rattus norvegicus), Mouse (Mus musculus) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of laminins with stabilizing Type IV collagen networks, Basement membranes are found under epithelial layers, Each laminin is a heterotrimer of a, Formation of basement membranes influences cell proliferation, Laminins can self-assemble, Nidogen, The human Laminin a-4 gene maps to chromosome 6q21 and is expressed in adult heart, and cognate laminin receptors, and fat cells, and g chain subunits that undergoes cell-secretion and incorporation into the ECM, and have unique and shared cell interactions mediated by integrins, and placenta, and several proteoglycans, and surrounding muscle, and tissue architecture, around the endothelium of blood vessels, b, bind to other matrix macromolecules, dystroglycan, gene expression, liver, lung, migration, ovary, peripheral nerve, phenotype, small and large intestines, Laminins are essential and abundant structural non-collagenous glyco- proteins localizing to basement membranes |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAMA3 |
| Also known as: |
Laminin alpha 4 Polyclonal Antibody |
| Other name: |
Anti-Laminin alpha 4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Laminin alpha 4 |
| Short name: |
Anti-Laminin alpha 4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Laminin a 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
6484 |
| Gene: |
LAMA4 |
More about : LAMA4 |
| Long gene name: |
laminin subunit alpha 4 |
| Synonyms gene name: |
alpha 4 , laminin |
| Locus: |
6q21 |
| Discovery year: |
1993-07-26 |
| Entrez gene record: |
3910 |
| Pubmed identfication: |
7959779 |
| RefSeq identity: |
NM_001105206 |
| Classification: |
Laminin subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000015386 |
| Locus Specific Databases: |
LRG_433 |