| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
LAMA3/Laminin 5 alpha 3 |
| Specificity: |
This antibody reacts specifically with LAMA3/Laminin 5 alpha 3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted, Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human LAMA3 |
| Gene ID: |
3909 |
| Swiss Prot: |
Q16787 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
(2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes, Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components, Binding to cells via a high affinity receptor |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
LAMA3 |
| Also known as: |
LAMA3/Laminin 5 alpha 3 Antibody |
| Other name: |
Anti-LAMA3/Laminin 5 alpha 3 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
LAMA3/Laminin 5 alpha 3 |
| Short name: |
Fluor 594, Anti-LAMA3/Laminin 5 alpha 3 |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, alpha 3/Laminin 5 a 3, antibody to-laminin |
| Alternative to gene target: |
BM600 and E170 and lama3a and LAMNA and LOCS, DNA-templated and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0008544 and epidermis development and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030155 and regulation of cell adhesion and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0031581 and hemidesmosome assembly and biological process this GO :0034329 and cell junction assembly and biological process this GO :0045995 and regulation of embryonic development and biological process, Extracellular, LAMA3 and IDBG-1631 and ENSG00000053747 and 3909, LAMA3 and IDBG-643892 and ENSBTAG00000027181 and 100336873, Lama3 and IDBG-128959 and ENSMUSG00000024421 and 16774, alpha 3, protein binding, this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005604 and basement membrane and cellular component this GO :0005606 and laminin-1 complex and cellular component this GO :0005610 and laminin-5 complex and cellular component this GO :0006355 and regulation of transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0004871 : signal transducer activity and also this GO :0005102 : receptor binding and also this GO :0005198 : structural molecule activity and also this GO :0005515 : protein binding, this GO :0004871 : signal transducer activity, this GO :0005102 : receptor binding, this GO :0005198 : structural molecule activity, this GO :0005515 : protein binding, laminin |
| Identity: |
6484 |
| Gene: |
LAMA4 |
More about : LAMA4 |
| Long gene name: |
laminin subunit alpha 4 |
| Synonyms gene name: |
alpha 4 , laminin |
| Locus: |
6q21 |
| Discovery year: |
1993-07-26 |
| Entrez gene record: |
3910 |
| Pubmed identfication: |
7959779 |
| RefSeq identity: |
NM_001105206 |
| Classification: |
Laminin subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000015386 |
| Locus Specific Databases: |
LRG_433 |