| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Thrombin Activation peptide fragment 2 |
| Specificity: |
This antibody reacts specifically with Thrombin Activation peptide fragment 2 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Thrombin Activation peptide fragment 2 |
| Gene ID: |
2147 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Glycosaminoglycan binding to exosite II of thrombin plays a major role in switching off the procoagulant functions of thrombin by mediating its irreversible inhibition by circulating serpins and by its binding to the endothelial cell surface receptor thrombomodulin, The ability of thrombin to specifically recognize a wide range of substrates derives from interactions which occur outside of the active site of thrombin, Thrombin possesses two anion binding exosites which mediate many of its interactions with cofactors and substrates, and although many structures of thrombin have been solved, few such interactions have been described in molecular detail, Thrombin is the final protease in the blood coagulation cascade and serves both pro- and anticoagulant functions through the cleavage of several targets |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Cf-2, Cf2, Coagulation factor II, Coagulation factor II precursor, F 2, F2, F2, FII, Factor II, Factor-II, PT, Prothrombin, THRB, THRB_HUMAN, Thrombin, coagulation factor II, coagulation factor II thrombin, prothrombin, prothrombin B-chain, serine protease, Activation peptide fragment 2 |
| Also known as: |
Thrombin Activation peptide fragment 2 Antibody |
| Other name: |
Anti-Thrombin Activation peptide fragment 2 |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Description: |
, The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs, The shortest peptides are dipeptides, These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), and unbranched synthetic peptide chains, consisting of 2 amino acids joined by a single peptide bond, continuous, followed by tripeptides, or in continue produced for custom peptide synthesis projects, tetra peptides, till polypeptides that are long, Peptides short amino acid chains or epitopes or blocking antagonists |
| Gene target: |
Thrombin Activation peptide 2 |
| Short name: |
Fluor 594, Anti-Thrombin Activation peptide 2 |
| Technique: |
peptides, peptide |
| Isotype: |
Complement fragments, Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small, IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion, bp DNA fragments are common, coli expressed, single chain variable fragments can be E, Antibody fragments and scFv fragments |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Thrombin Activation short protein sequence fragment 2 |
| Alternative technique: |
peptides |