| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Nectin 4 |
| Specificity: |
This antibody reacts specifically with Nectin 4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Nectin 4 |
| Gene ID: |
59341 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined, It is a single-pass type I membrane protein, It is involved in cell adhesion through trans-homophilic and -heterophilic interactions, Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain, The secreted form is found in both breast tumor cell lines and breast tumor patients, The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE, an autosomal recessive disorder, This gene encodes a member of the nectin family |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
nectin-4 PRR4 LNIR |
| Also known as: |
Nectin 4 Polyclonal Antibody |
| Other name: |
Anti-Nectin 4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Nectin 4 |
| Short name: |
Anti-Nectin 4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Nectin 4 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
19688 |
| Gene: |
NECTIN4 |
More about : NECTIN4 |
| Long gene name: |
nectin cell adhesion molecule 4 |
| Synonyms gene: |
PVRL4 |
| Synonyms gene name: |
poliovirus receptor-related 4 |
| Locus: |
1q23, 3 |
| Discovery year: |
2004-02-11 |
| GenBank acession: |
AF426163 |
| Entrez gene record: |
81607 |
| Pubmed identfication: |
11544254 |
| RefSeq identity: |
NM_030916 |
| Classification: |
C2-set domain containing V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031475 |