| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Nectin 3 |
| Specificity: |
This antibody reacts specifically with Nectin 3 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Nectin 3 |
| Gene ID: |
25945 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
-2, -3 and -4, Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton, All the members of the nectin family have two or three slice variants, Nectin 3 is mainly expressed in testis and placental tissues and interacts in vivo with both long and short isoforms of afadin, The nectin-afadin system organizes adherens junctions cooperatively with the cadherin-catenin system in epithelial cells, nectin-1, Nectins are immunoglobulin-like adhesion molecules that interact with afadin, The nectin/PRR-family consists of four members |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
nectin-3 PPR3 PVRR3 DKFZP566B0846 CDw113 CD113 |
| Also known as: |
Nectin 3 Polyclonal Antibody |
| Other name: |
Anti-Nectin 3 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Nectin 3 |
| Short name: |
Anti-Nectin 3 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Nectin 3 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
17664 |
| Gene: |
NECTIN3 |
More about : NECTIN3 |
| Long gene name: |
nectin cell adhesion molecule 3 |
| Synonyms gene: |
PVRL3 |
| Synonyms gene name: |
poliovirus receptor-related 3 |
| Locus: |
3q13, 13 |
| Discovery year: |
2004-02-11 |
| GenBank acession: |
AF282874 |
| Entrez gene record: |
25945 |
| Pubmed identfication: |
11024295 |
| RefSeq identity: |
NM_015480 |
| Classification: |
C2-set domain containing I-set domain containing CD molecules V-set domain containing Immunoglobulin like domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000159239 |