| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ABL2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (FFPE): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the ABL2 antibody should be determined by the researcher |
| Intented use: |
This ABL2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P42684 |
| Purity: |
Antigen affinity |
| Description: |
Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene, SH2 and SH3 domains, The protein is highly similar to the c-abl oncogene 1 protein, This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases, This gene is expressed in both normal and tumor cells, also known as Abelson-related gene (Arg), and is involved in translocation with the ets variant 6 gene in leukemia, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences, including the tyrosine kinase, is an enzyme that in humans is encoded by the ABL2 gene, Tyrosine-protein kinase ABL2 |
| Immunogen: |
Amino acids T1065-R1182 of the human protein were used as the immunogen for the ABL2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ABL2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
membranous, nuclear, Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ABL2 |
| Short name: |
ABL2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
v-abl Abelson murine leukemia viral oncogene homolog 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ABL2 and IDBG-105099 and ENSG00000143322 and 27, ABLL and ARG, Abl2 and IDBG-200390 and ENSMUSG00000026596 and 11352, BT, Cytoplasm, this GO :0000287 and magnesium ion binding and molecular function this GO :0003785 and actin monomer binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007015 and actin filament organization and biological process this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0010506 and regulation of autophagy and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016772 and transferase activity, this GO :0000287 : magnesium ion binding, this GO :0000287 : magnesium ion binding and also this GO :0003785 : actin monomer binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0003785 : actin monomer binding, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, this GO :0030145 : manganese ion binding, this GO :0051015 : actin filament binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030145 : manganese ion binding and also this GO :0051015 : actin filament binding, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030100 and regulation of endocytosis and biological process this GO :0030145 and manganese ion binding and molecular function this GO :0030155 and regulation of cell adhesion and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051017 and actin filament bundle assembly and biological process this GO :0051353 and positive regulation of oxidoreductase activity and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :2000145 and regulation of cell motility and biological process this GO :2000249 and regulation of actin cytoskeleton reorganization and biological process, 62162 and IDBG-636736 and ENSBTAG00000015026 and 511845, v-abl Abelson murine leukemia viral oncogene homolog 2 |
| Identity: |
77 |
| Gene: |
ABL2 |
More about : ABL2 |
| Long gene name: |
ABL proto-oncogene 2, non-receptor tyrosine kinase |
| Synonyms gene: |
ABLL |
| Synonyms gene name: |
Abelson-related gene) v-abl Abelson murine leukemia viral oncogene homolog 2 c-abl oncogene 2, non-receptor tyrosine kinase , v-abl Abelson murine leukemia viral oncogene homolog 2 (arg |
| Synonyms: |
ARG |
| Synonyms name: |
Abelson-related gene |
| Locus: |
1q25, 2 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M14904 |
| Entrez gene record: |
27 |
| Pubmed identfication: |
3787260 |
| RefSeq identity: |
NM_005158 |
| Classification: |
SH2 domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000035199 |