| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
JAB1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the JAB1 antibody should be determined by the researcher |
| Intented use: |
This JAB1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q92905 |
| Purity: |
Antigen affinity |
| Description: |
COPS5, COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, COPS5 is an essential cofactor for the apoptotic function of E2F1, COPS5 is mapped to 8q13, In addition to that, It is a member of the MOV34 family, The protein encoded by this gene is one of the eight subunits of COP9 signalosome, VHL, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways, also known as COPS5 or JAB1, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer, and it is the only protein demonstrated to interact with MIF, is a gene conserved from humans to Saccharomyces cerevisiae, 1, COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) |
| Immunogen: |
Amino acids 8-334 of human JAB1 were used as the immunogen for the JAB1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the JAB1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Nuclear and cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
JAB1 |
| Short name: |
JAB1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
JAB1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2240 |
| Gene: |
COPS5 |
More about : COPS5 |
| Long gene name: |
COP9 signalosome subunit 5 |
| Synonyms gene name: |
Arabidopsis, COP9 (constitutive photomorphogenic, homolog) subunit 5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) |
| Synonyms: |
JAB1 SGN5 MOV-34 CSN5 |
| Locus: |
8q13, 1 |
| Discovery year: |
2000-06-08 |
| GenBank acession: |
U65928 |
| Entrez gene record: |
10987 |
| Pubmed identfication: |
8837781 9341143 |
| Classification: |
COP9 signalosome |
| Havana BLAST/BLAT: |
OTTHUMG00000164563 |