| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RAR Beta |
| Specificity: |
This antibody reacts specifically with RAR Beta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus, Cytoplasm |
| Antigen Source: |
KLH conjugated synthetic peptide derived from mouse RAR Beta |
| Gene ID: |
5915 |
| Swiss Prot: |
P10826 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
In concert with RARG, In the absence or presence of hormone ligand, Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5, acts mainly as an activator of gene expression due to weak binding to corepressors, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes, matrix homeostasis and growth plate function, required for skeletal growth, Receptor for retinoic acid |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
RAR NR1B1 |
| Also known as: |
RAR Beta Polyclonal Antibody |
| Other name: |
Anti-RAR Beta Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RAR Beta |
| Short name: |
Anti-RAR Beta (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-RAR b (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
9864 |
| Gene: |
RARA |
More about : RARA |
| Long gene name: |
retinoic acid receptor alpha |
| Synonyms gene name: |
alpha , retinoic acid receptor |
| Locus: |
17q21, 2 |
| Discovery year: |
1988-06-09 |
| GenBank acession: |
X06538 |
| Entrez gene record: |
5914 |
| Pubmed identfication: |
2825036 8244378 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133328 |
| Locus Specific Databases: |
LRG_1070 |