| known also as: |
Anti-RABBIT ANTI HUMAN RAR BETA (C-TERMINAL) |
| known also as: |
RABBIT ANTI HUMAN RAR BETA (C-TERMINAL) |
| known also as: |
Lapin ANTI Homo sapiens RAR BETA (C-TERMINAL) |
| known also as: |
RAR BETA |
| Other names: |
HBV-activated protein, HBV-activated protein, Nuclear receptor subfamily 1 group B member 2, RAR-beta, RAR-epsilon, RAR-epsilon, Retinoic acid receptor beta, beta, beta polypeptide, hepatitis B virus activated protein, nuclear receptor subfamily 1 group B member 2, retinoic acid receptor, retinoic acid receptor, retinoic acid receptor beta, retinoic acid receptor beta 2, retinoic acid receptor beta 4, retinoic acid receptor beta 5, retinoic acid receptor beta variant 1, retinoic acid receptor beta variant 2, retinoic acid receptor beta isoform 1 |
| Gene name: |
RAR BETA |
| Other gene names: |
HAP, HAP, NR1B2, NR1B2, RAR-beta, RARB, RRB2, RARB |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
Down-regulation of the RAR-b2 isoform occurs early in tumorigenesis, In this way RAR beta mediates cellular signalling in embryonic morphogenesis and organogenesis, Once activated RAR beta heterodimerizes with retinoid X receptors (RXRs) and translocates to the nucleus, _x000D__x000D_The RAR beta exists as three isoforms, a 55kD transcriptional factor which is activated by retinoic acid, and is a tumour suppressor gene, differentiation-inducing genes, where it stimulates the transcription of growth-inhibitory, which are localised to the cytoplasm or subnuclear compartments, RAR BETA This item detects an epitope within the C-terminal (CT) of retinoic acid receptor beta (RAR beta) |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
2 mg/ml, IgG concentration 0 |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
Immunohistology - Paraffin (IHC) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target: |
RAR BETA |
| Short name: |
Anti-HUMAN RAR BETA (C-TERMINAL) |
| Alternative name: |
sapiens RAR b (C-TERMINAL), antibody to-H |
| Identity: |
9864 |
| Gene: |
RARA |
More about : RARA |
| Long gene name: |
retinoic acid receptor alpha |
| Synonyms gene name: |
alpha , retinoic acid receptor |
| Synonyms: |
RAR NR1B1 |
| Locus: |
17q21, 2 |
| Discovery year: |
1988-06-09 |
| GenBank acession: |
X06538 |
| Entrez gene record: |
5914 |
| Pubmed identfication: |
2825036 8244378 |
| Classification: |
Nuclear hormone receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000133328 |
| Locus Specific Databases: |
LRG_1070 |