| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FCGRT |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Optimal dilution of the FCGRT antibody should be determined by the researcher |
| Intented use: |
This FCGRT antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P55899 |
| Purity: |
Antigen affinity |
| Description: |
In addition, The FCGRT gene is closely situated to the DMPK gene, The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta, This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G, This protein also binds immunoglobulin G to protect the antibody from degradation, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy, which is mutant in DM, IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene |
| Immunogen: |
Amino acids 56-291 of human FCGRT were used as the immunogen for the FCGRT antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FCGRT antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FCGRT |
| Short name: |
FCGRT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
alpha (Antibody to), receptor, transporter, fragment c fragment on Immunoglobulin G |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FCGRT and IDBG-63001 and ENSG00000104870 and 2217, FCGRT and IDBG-640575 and ENSBTAG00000013926 and 338062, Fcgrt and IDBG-181534 and ENSMUSG00000003420 and 14132, Plasma membranes, alpha, alpha-chain and FCRN, beta-2-microglobulin binding, receptor, this GO :0002416 and IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019864 and IgG binding and molecular function this GO :0019882 and antigen processing and presentation and biological process this GO :0030881 and beta-2-microglobulin binding and molecular function this GO :0038094 and Fc-gamma receptor signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0019864 : IgG binding and also this GO :0030881 : beta-2-microglobulin binding, this GO :0019864 : IgG binding, this GO :0030881 : beta-2-microglobulin binding, transporter, Fc fragment of IgG |
| Identity: |
3621 |
| Gene: |
FCGRT |
More about : FCGRT |
| Long gene name: |
Fc fragment of IgG receptor and transporter |
| Synonyms gene name: |
Fc fragment of IgG, alpha , receptor, transporter |
| Synonyms: |
FCRN alpha-chain |
| Synonyms name: |
heavy chain of the major histocompatibility complex class I-like Fc receptor transmembrane alpha chain of the neonatal receptor |
| Locus: |
19q13, 33 |
| Discovery year: |
1995-08-23 |
| GenBank acession: |
U12255 |
| Entrez gene record: |
2217 |
| Pubmed identfication: |
7964511 8646894 |
| Classification: |
C1-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000183155 |