| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
WASP |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Optimal dilution of the WASP antibody should be determined by the researcher |
| Intented use: |
This WASP antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P42768 |
| Purity: |
Antigen affinity |
| Description: |
A transcript variant arising as a result of alternative promoter usage, Arp2/3, Cdc42, Recent studies have demonstrated that these proteins, The WAS gene product is a cytoplasmic protein, The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, Wiskott-Aldrich syndrome is a rare, X-linked, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton, and containing a different 5' UTR sequence, and interact with multiple proteins, and is caused by mutations in the WAS gene, and the cytoskeletal organizing complex, associate with the small GTPase, directly or indirectly, expressed exclusively in hematopoietic cells, has been described, however, inherited, its full-length nature is not known, known to regulate formation of actin filaments, recessive disease characterized by immune dysregulation and microthrombocytopenia, which show signalling and cytoskeletal abnormalities in WAS patients, The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure |
| Immunogen: |
Amino acids ADEDEAQAFRALVQEKIQKRNQRQSGDR of human WASP were used as the immunogen for the WASP antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the WASP antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Localization: |
Cytoplasmic |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
WASP |
| Short name: |
WASP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
WASP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12731 |
| Gene: |
WAS |
More about : WAS |
| Long gene name: |
Wiskott-Aldrich syndrome |
| Synonyms gene: |
IMD2 THC |
| Synonyms gene name: |
thrombocytopenia 1 (X-linked) Wiskott-Aldrich syndrome (eczema-thrombocytopenia) |
| Synonyms: |
WASP WASPA |
| Synonyms name: |
eczema-thrombocytopenia |
| Locus: |
Xp11, 23 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AF115548 |
| Entrez gene record: |
7454 |
| Pubmed identfication: |
7795648 |
| RefSeq identity: |
NM_000377 |
| Classification: |
Wiskott-Aldrich Syndrome protein family |
| Havana BLAST/BLAT: |
OTTHUMG00000034483 |
| Locus Specific Databases: |
WASbase: Mutation registry for Wiskott-Aldrich syndrome (WAS) LRG_125 |