| known also as: |
Eczema-thrombocytopenia), IMD2, N- (WAS, THC, WASP, Anti-WASP |
| known also as: |
Eczema-thrombocytopenia), IMD2, N- (WAS, THC, WASP, WASP |
| known also as: |
Eczema-thrombocytopenia), IMD2, N- (WAS, THC, WASP, WASP |
| known also as: |
N-, WASP |
| known also as: |
Eczema-thrombocytopenia), IMD2, N- (WAS, THC, WASP, Anti -WASP |
| Other names: |
N/A, Wiskott-Aldrich syndrome protein |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Source: Human, Host: Rabbit |
| Species reactivity: |
Rat, Human |
| Specificity and cross-reactivity: |
Also has a low homology to human WASP, Detects a 65kD protein corresponding to the molecular mass of N-WASP on SDS-PAGE immunoblots of neonatal rat brain lysate, It does not recognize the 63kD WASP protein in Jurkat cell lysate, It is also detects 65kD proteins in A431, Species sequence homology: rat and mouse, and SKN-SH cells, human endothelial, Recognizes human N-WASP |
| Purification method: |
Affinity Purified by immunoaffinity chromatography |
| Form/Appearance: |
0, 1mg/ml BSA, 50% glycerol, 05% sodium azide, Supplied as a liquid in PBS |
| Storage and shipping: |
For maximum recovery of product, Further dilutions can be made in assay buffer, Long-term storage should be done after aliquoting the item and freezing the aliqotes at -20 degrees Celsius, Under these conditions the aliquots will be stable for at least one year if kept at -20 °, centrifuge the original vial after thawing and prior to removing the cap, C, Store at 4 degrees Celsius for short term storage |
| Tested for:: |
Western Blot (WB), ELISA (EL/EIA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
Eczema-thrombocytopenia), IMD2, N (WAS, THC, WASP, WASP |
| Short name: |
Eczema-thrombocytopenia) Antibody, IMD2, N- (WAS, THC, WASP, WASP |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Eczema-thrombocytopenia) (Antibody to), IMD2, N- (Wiskott-Aldrich syndrome, THC, WASP, WASP |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, IMD2 and SCNX and THC and THC1 and WASP, WAS and IDBG-636860 and ENSBTAG00000046555 and, WAS and IDBG-63703 and ENSG00000015285 and 7454, Was and IDBG-130090 and ENSMUSG00000031165 and 22376, identical protein binding, this GO :0003779 and actin binding and molecular function this GO :0005083 and small GTPase regulator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006952 and defense response and biological process this GO :0006955 and immune response and biological process this GO :0007015 and actin filament organization and biological process this GO :0007596 and blood coagulation and biological process this GO :0008154 and actin polymerization or depolymerization and biological process this GO :0008544 and epidermis development and biological process this GO :0012506 and vesicle membrane and cellular component this GO :0015629 and actin cytoskeleton and cellular component this GO :0016197 and endosomal transport and biological process this GO :0030041 and actin filament polymerization and biological process this GO :0030048 and actin filament-based movement and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042110 and T cell activation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0050790 and regulation of catalytic activity and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :2000601 and positive regulation of Arp2/3 complex-mediated actin nucleation and biological process, this GO :0003779 : actin binding, this GO :0003779 : actin binding and also this GO :0005083 : small GTPase regulator activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0005083 : small GTPase regulator activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, Wiskott-Aldrich syndrome |
| Identity: |
12731 |
| Gene: |
WAS |
More about : WAS |
| Long gene name: |
Wiskott-Aldrich syndrome |
| Synonyms gene: |
IMD2 THC |
| Synonyms gene name: |
thrombocytopenia 1 (X-linked) Wiskott-Aldrich syndrome (eczema-thrombocytopenia) |
| Synonyms: |
WASP WASPA |
| Synonyms name: |
eczema-thrombocytopenia |
| Locus: |
Xp11, 23 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
AF115548 |
| Entrez gene record: |
7454 |
| Pubmed identfication: |
7795648 |
| RefSeq identity: |
NM_000377 |
| Classification: |
Wiskott-Aldrich Syndrome protein family |
| Havana BLAST/BLAT: |
OTTHUMG00000034483 |
| Locus Specific Databases: |
WASbase: Mutation registry for Wiskott-Aldrich syndrome (WAS) LRG_125 |