| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CCL3 / MIP-1 alpha |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, WB |
| Recommended dilutions: |
1-0, 1-0, 5ug/ml, 5ug/ml, ELISA : 0, Western blot: 0 |
| Notes: |
Optimal dilution of the CCL3 antibody should be determined by the researcher |
| Intented use: |
This CCL3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P10147 |
| Purity: |
Antigen affinity |
| Description: |
CCL3 is a chemokine that has pro-inflammatory and stem cell inhibitory activities in vitro, CCL3 is a member of a newly identified superfamily of small inducible proteins involved in inflammatory responses, It constitutes an important second signal for mast cell degranulation in the conjunctiva in vivo and consequently for acute-phase disease, LD78, The cDNA for CCL3 predicts a mature peptide of 69 amino acids with a molecular mass of 7, also called CCL3, wound healing and tumorigenesis, 889 daltons, Macrophage inflammatory protein-1 alpha (MIP-1 alpha) |
| Immunogen: |
Amino acids 24-92 of human CCL3 were used as the immunogen for the CCL3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CCL3 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CCL3 / MIP-1 alpha |
| Short name: |
CCL3 Antibody / MIP-1 alpha |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-C motif) ligand 3 (Antibody to) / MIP-1 a |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CCL3 and IDBG-776925 and ENSG00000277632 and 6348, Extracellular, G0S19-1 and LD78ALPHA and MIP-1-alpha and MIP1A and SCYA3, identical protein binding, this GO :0000165 and MAPK cascade and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001775 and cell activation and biological process this GO :0002548 and monocyte chemotaxis and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004698 and calcium-dependent protein kinase C activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006874 and cellular calcium ion homeostasis and biological process this GO :0006887 and exocytosis and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007010 and cytoskeleton organization and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0007610 and behavior and biological process this GO :0008009 and chemokine activity and molecular function this GO :0008360 and regulation of cell shape and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010629 and negative regulation of gene expression and biological process this GO :0010818 and T cell chemotaxis and biological process this GO :0014808 and release of sequestered calcium ion into cytosol by sarcoplasmic reticulum and biological process this GO :0016004 and phospholipase activator activity and molecular function this GO :0016301 and kinase activity and molecular function this GO :0019722 and calcium-mediated signaling and biological process this GO :0023052 and signaling and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030502 and negative regulation of bone mineralization and biological process this GO :0030593 and neutrophil chemotaxis and biological process this GO :0031663 and lipopolysaccharide-mediated signaling pathway and biological process this GO :0031726 and CCR1 chemokine receptor binding and molecular function this GO :0031730 and CCR5 chemokine receptor binding and molecular function this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0042056 and chemoattractant activity and molecular function this GO :0042802 and identical protein binding and molecular function this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043308 and eosinophil degranulation and biological process this GO :0043491 and protein kinase B signaling and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043615 and astrocyte cell migration and biological process this GO :0043922 and negative regulation by host of viral transcription and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0048245 and eosinophil chemotaxis and biological process this GO :0048246 and macrophage chemotaxis and biological process this GO :0048247 and lymphocyte chemotaxis and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050729 and positive regulation of inflammatory response and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050918 and positive chemotaxis and biological process this GO :0051897 and positive regulation of protein kinase B signaling and biological process this GO :0051928 and positive regulation of calcium ion transport and biological process this GO :0051930 and regulation of sensory perception of pain and biological process this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070723 and response to cholesterol and biological process this GO :0071346 and cellular response to interferon-gamma and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071621 and granulocyte chemotaxis and biological process this GO :0090280 and positive regulation of calcium ion import and biological process this GO :2000503 and positive regulation of natural killer cell chemotaxis and biological process, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004698 : calcium-dependent protein kinase C activity and also this GO :0005515 : protein binding and also this GO :0008009 : chemokine activity and also this GO :0016004 : phospholipase activator activity and also this GO :0016301 : kinase activity and also this GO :0031726 : CCR1 chemokine receptor binding and also this GO :0031730 : CCR5 chemokine receptor binding and also this GO :0042056 : chemoattractant activity and also this GO :0042802 : identical protein binding, this GO :0004698 : calcium-dependent protein kinase C activity, this GO :0005515 : protein binding, this GO :0008009 : chemokine activity, this GO :0016004 : phospholipase activator activity, this GO :0016301 : kinase activity, this GO :0031726 : CCR1 chemokine receptor binding, this GO :0031730 : CCR5 chemokine receptor binding, this GO :0042056 : chemoattractant activity, this GO :0042802 : identical protein binding, chemokine (C-C motif) ligand 3 |
| Identity: |
10627 |
| Gene: |
CCL3 |
More about : CCL3 |
| Long gene name: |
C-C motif chemokine ligand 3 |
| Synonyms gene: |
SCYA3 |
| Synonyms gene name: |
small inducible cytokine A3 (homologous to mouse Mip-1a) chemokine (C-C motif) ligand 3 |
| Synonyms: |
G0S19-1 LD78ALPHA MIP-1-alpha |
| Locus: |
17q12 |
| Discovery year: |
1990-07-05 |
| GenBank acession: |
M23178 |
| Entrez gene record: |
6348 |
| RefSeq identity: |
NM_002983 |
| Classification: |
Endogenous ligands Chemokine ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000188413 |