| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ADRB2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the ADRB2 antibody should be determined by the researcher |
| Intented use: |
This ADRB2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P07550 |
| Purity: |
Antigen affinity |
| Description: |
It is mapped to 5q32, The genetic variation in the ADRB2 gene may be of major importance for obesity, This receptor is directly associated with one of its ultimate effectors, What&rsquo, also known as beta-2 adrenergic receptor, and lipolytic ADRB2 function in adipose tissue, and the ADRB2 receptors activator may contribute to beta-amyloid accumulation in AD, at least in women, energy expenditure, is a beta-adrenergic receptor within a cell membrane which reacts with adrenaline (epinephrine) as a hormone or neurotransmitter affecting muscles or organs, it has been found that activation of ADRB2 receptors can stimulate gamma-secretase activity and beta-amyloid production, the class C L-type calcium channel Ca(V)1, 2, ADRB2, s more |
| Immunogen: |
Amino acids RVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGH of human ADRB2 were used as the immunogen for the ADRB2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ADRB2 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ADRB2 |
| Short name: |
ADRB2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
surface (Antibody to), adrenoceptor b 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADRB2 and IDBG-52685 and ENSG00000169252 and 154, ADRB2 and IDBG-648668 and ENSBTAG00000002144 and 281605, ADRB2R and ADRBR and B2AR and BAR and BETA2AR, Adrb2 and IDBG-152615 and ENSMUSG00000045730 and 11555, norepinephrine binding, nuclei, surface, this GO :0001993 and regulation of systemic arterial blood pressure by norepinephrine-epinephrine and biological process this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0002032 and desensitization of G-protein coupled receptor protein signaling pathway by arrestin and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004941 and beta2-adrenergic receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0008179 and adenylate cyclase binding and molecular function this GO :0008333 and endosome to lysosome transport and biological process this GO :0009409 and response to cold and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031649 and heat generation and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042312 and regulation of vasodilation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045453 and bone resorption and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051380 and norepinephrine binding and molecular function this GO :0071875 and adrenergic receptor signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004941 : beta2-adrenergic receptor activity and also this GO :0005515 : protein binding and also this GO :0008179 : adenylate cyclase binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0019899 : enzyme binding and also this GO :0042803 : protein homodimerization activity and also this GO :0051380 : norepinephrine binding, this GO :0004941 : beta2-adrenergic receptor activity, this GO :0005515 : protein binding, this GO :0008179 : adenylate cyclase binding, this GO :0015459 : potassium channel regulator activity, this GO :0019899 : enzyme binding, this GO :0042803 : protein homodimerization activity, this GO :0051380 : norepinephrine binding, adrenoceptor beta 2 |
| Identity: |
286 |
| Gene: |
ADRB2 |
More about : ADRB2 |
| Long gene name: |
adrenoceptor beta 2 |
| Synonyms gene: |
ADRB2R |
| Synonyms gene name: |
adrenergic, beta-2-, receptor, surface , surface adrenoceptor beta 2 |
| Synonyms: |
ADRBR BAR B2AR |
| Locus: |
5q32 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
AF022953 |
| Entrez gene record: |
154 |
| RefSeq identity: |
NM_000024 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000129933 |