| Long name: |
ADRB2 (Ser261) Primary Polyclonal Antibody |
| Also known as: |
ADRB2 (Ser261) PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
ADRB2 Ser261 |
| Specificity: |
This is a highly specific antibody against ADRB2 Ser261 |
| Modification(s): |
Phosphorylation |
| Modification site(s): |
Ser261 |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser261 |
| Gene ID number: |
154 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Different polymorphic forms, Expression of the beta 2 Adrenergic Receptor has been reported in adipose, PP2A, The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor, This gene contains no introns in either its coding or untranslated sequences, This receptor channel complex also contains a G protein, This receptor is directly associated with one of its ultimate effectors, an adenylyl cyclase, and the counterbalancing phosphatase, and vessel, and/or downregulation of this gene are associated with nocturnal asthma, blood, brain, cAMP dependent kinase, heart, lung, nose, obesity and type 2 diabetes, pancreas, point mutations, skeletal muscle, skin, the class C L type calcium channel Ca(V)1, 2, Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ADRB2, ADRB2R, ADRB2_HUMAN, ADRBR, Adrenergic beta 2 receptor surface, B2AR, BAR, BETA2AR, Beta 2 adrenoreceptor, Catecholamine receptor, beta 2 adrenoceptor, beta2-adrenergic receptor, 2-adrenergic receptor |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADRB2 (Ser261) |
| Short name: |
ADRB2 (Ser261) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
surface (Ser261) (Antibody to), adrenoceptor b 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADRB2 and IDBG-52685 and ENSG00000169252 and 154, ADRB2 and IDBG-648668 and ENSBTAG00000002144 and 281605, ADRB2R and ADRBR and B2AR and BAR and BETA2AR, Adrb2 and IDBG-152615 and ENSMUSG00000045730 and 11555, norepinephrine binding, nuclei, surface, this GO :0001993 and regulation of systemic arterial blood pressure by norepinephrine-epinephrine and biological process this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0002032 and desensitization of G-protein coupled receptor protein signaling pathway by arrestin and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004941 and beta2-adrenergic receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0008179 and adenylate cyclase binding and molecular function this GO :0008333 and endosome to lysosome transport and biological process this GO :0009409 and response to cold and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031649 and heat generation and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042312 and regulation of vasodilation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045453 and bone resorption and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051380 and norepinephrine binding and molecular function this GO :0071875 and adrenergic receptor signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004941 : beta2-adrenergic receptor activity and also this GO :0005515 : protein binding and also this GO :0008179 : adenylate cyclase binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0019899 : enzyme binding and also this GO :0042803 : protein homodimerization activity and also this GO :0051380 : norepinephrine binding, this GO :0004941 : beta2-adrenergic receptor activity, this GO :0005515 : protein binding, this GO :0008179 : adenylate cyclase binding, this GO :0015459 : potassium channel regulator activity, this GO :0019899 : enzyme binding, this GO :0042803 : protein homodimerization activity, this GO :0051380 : norepinephrine binding, adrenoceptor beta 2 |
| Identity: |
286 |
| Gene: |
ADRB2 |
More about : ADRB2 |
| Long gene name: |
adrenoceptor beta 2 |
| Synonyms gene: |
ADRB2R |
| Synonyms gene name: |
adrenergic, beta-2-, receptor, surface , surface adrenoceptor beta 2 |
| Synonyms: |
ADRBR BAR B2AR |
| Locus: |
5q32 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
AF022953 |
| Entrez gene record: |
154 |
| RefSeq identity: |
NM_000024 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000129933 |