| Long name: |
Biotin Conjugated, ADRB2 (Ser261) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ADRB2 Ser261 |
| Specificity: |
This is a highly specific antibody against ADRB2 Ser261 |
| Modification: |
Phosphorylation |
| Modification site: |
Ser261 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser261 |
| Gene ID number: |
154 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Different polymorphic forms, Expression of the beta 2 Adrenergic Receptor has been reported in adipose, PP2A, The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein coupled receptor, This gene contains no introns in either its coding or untranslated sequences, This receptor channel complex also contains a G protein, This receptor is directly associated with one of its ultimate effectors, an adenylyl cyclase, and the counterbalancing phosphatase, and vessel, and/or downregulation of this gene are associated with nocturnal asthma, blood, brain, cAMP dependent kinase, heart, lung, nose, obesity and type 2 diabetes, pancreas, point mutations, skeletal muscle, skin, the class C L type calcium channel Ca(V)1, 2, Beta 2 Adrenergic Receptor is a member of the G protein coupled receptor superfamily |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ADRBR BAR B2AR |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ADRB2 (Ser261) Conjugated |
| Short name: |
Conjugated, ADRB2 (Ser261) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, surface (Ser261) (Antibody to), adrenoceptor b 2 |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ADRB2 and IDBG-52685 and ENSG00000169252 and 154, ADRB2 and IDBG-648668 and ENSBTAG00000002144 and 281605, ADRB2R and ADRBR and B2AR and BAR and BETA2AR, Adrb2 and IDBG-152615 and ENSMUSG00000045730 and 11555, norepinephrine binding, nuclei, surface, this GO :0001993 and regulation of systemic arterial blood pressure by norepinephrine-epinephrine and biological process this GO :0002024 and diet induced thermogenesis and biological process this GO :0002025 and vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0002032 and desensitization of G-protein coupled receptor protein signaling pathway by arrestin and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004941 and beta2-adrenergic receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007171 and activation of transmembrane receptor protein tyrosine kinase activity and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007188 and adenylate cyclase-modulating G-protein coupled receptor signaling pathway and biological process this GO :0007189 and adenylate cyclase-activating G-protein coupled receptor signaling pathway and biological process this GO :0007190 and activation of adenylate cyclase activity and biological process this GO :0008179 and adenylate cyclase binding and molecular function this GO :0008333 and endosome to lysosome transport and biological process this GO :0009409 and response to cold and biological process this GO :0015459 and potassium channel regulator activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031398 and positive regulation of protein ubiquitination and biological process this GO :0031649 and heat generation and biological process this GO :0040015 and negative regulation of multicellular organism growth and biological process this GO :0042312 and regulation of vasodilation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0045087 and innate immune response and biological process this GO :0045453 and bone resorption and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0050873 and brown fat cell differentiation and biological process this GO :0051380 and norepinephrine binding and molecular function this GO :0071875 and adrenergic receptor signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004941 : beta2-adrenergic receptor activity and also this GO :0005515 : protein binding and also this GO :0008179 : adenylate cyclase binding and also this GO :0015459 : potassium channel regulator activity and also this GO :0019899 : enzyme binding and also this GO :0042803 : protein homodimerization activity and also this GO :0051380 : norepinephrine binding, this GO :0004941 : beta2-adrenergic receptor activity, this GO :0005515 : protein binding, this GO :0008179 : adenylate cyclase binding, this GO :0015459 : potassium channel regulator activity, this GO :0019899 : enzyme binding, this GO :0042803 : protein homodimerization activity, this GO :0051380 : norepinephrine binding, adrenoceptor beta 2 |
| Identity: |
286 |
| Gene: |
ADRB2 |
More about : ADRB2 |
| Long gene name: |
adrenoceptor beta 2 |
| Synonyms gene: |
ADRB2R |
| Synonyms gene name: |
adrenergic, beta-2-, receptor, surface , surface adrenoceptor beta 2 |
| Locus: |
5q32 |
| Discovery year: |
1990-09-10 |
| GenBank acession: |
AF022953 |
| Entrez gene record: |
154 |
| RefSeq identity: |
NM_000024 |
| Classification: |
Adrenoceptors |
| Havana BLAST/BLAT: |
OTTHUMG00000129933 |