p95 NBS1 Antibody

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Catalog number: R31829
Price: 255 €
Supplier: genways
Product name: p95 NBS1 Antibody
Quantity: 1 vial
Other quantities: 0.1ml 263€ 50ug 470€
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Category: Antibody
Concentration: 2ml sterile DI water, 5mg/ml if reconstituted with 0
Form: Antigen affinity purified
Conjugation: Unconjugated
Clone: Polyclonal antibody
Recognised antigen: p95 NBS1
Host animal: Rabbit (Oryctolagus cuniculus)
Clonality: Polyclonal (rabbit origin)
Species reactivity: Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications: IHC-P, WB
Recommended dilutions: 1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes: Optimal dilution of the p95 NBS1 antibody should be determined by the researcher
Intented use: This p95 NBS1 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #: O60934
Purity: Antigen affinity
Description: It also has a role in regulation of N/M/R (MRN) protein complex activity which includes end-processing of both physiological and mutagenic DNA double strand breaks (DSBs), It is a 754 amino acid protein identified as a member of the NBS1/hMre11/RAD50 (N/M/R or MRN) double strand DNA break repair complex, Nibrin is a protein associated with the repair of double strand breaks (DSBs) which pose serious damage to a genome, This complex recognizes DNA damage and rapidly relocates to DSB sites and forms nuclear foci, also known as NBN or Nibrin, is a protein which in humans is encoded by the NBN gene, p95 NBS1
Immunogen: Amino acids RKNTELEEWLRQEMEVQNQHAKEESLADDLFR of human p95 NBS1 were used as the immunogen for the p95 NBS1 antibody
Storage: Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the p95 NBS1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
Localization: Nuclear
Properties: C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene target: p95 NBS1
Short name: p95 NBS1 Antibody
Technique: antibodies against human proteins, antibodies for, Antibody
Alternative name: p95 NBS1 (Antibody to)
Alternative technique: antibodies
Identity: 7652
Gene: NBN | More about : NBN
Long gene name: nibrin
Synonyms gene: NBS NBS1
Synonyms gene name: Nijmegen breakage syndrome 1 (nibrin)
Synonyms: ATV AT-V2 AT-V1
Locus: 8q21, 3
Discovery year: 1997-11-28
GenBank acession: AF058696
Entrez gene record: 4683
Pubmed identfication: 9590181 9590180
RefSeq identity: NM_001024688
Classification: BRCA1 C complex MRN complex
Havana BLAST/BLAT: OTTHUMG00000153546
Locus Specific Databases: LOVD - Leiden Open Variation Database LRG_158

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