| Category: |
Antibody |
| Concentration: |
01% sodium azide if reconstituted with 0, 2ml sterile 1XPBS, 5mg/ml with 1% BSA and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cyclin A (CCNA1) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Variations in secondary/substrate sensitivities and test protocols may require the Cyclin A antibody to be titrated for optimal performance |
| Intented use: |
This Cyclin A antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
890 |
| Purity: |
Antigen affinity |
| Description: |
Also this cyclin was found to bind to important cell cycle regulators, Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Multiple transcript variants encoding different isoforms have been found for this gene, The cyclin encoded by this gene was shown to be expressed in testis and brain, The protein encoded by this gene belongs to the highly conserved cyclin family, This cyclin binds both<, and is thought to primarily function in the control of the germline meiotic cell cycle, and the p21 family proteins, and thus regulate separate functions in cell cycle, as well as in several leukemic cell lines, one appearing in S phase, such as Rb family proteins, the other in G2, transcription factor E2F-1, which give two distinct kinase activities, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, /a>, /search_result, CDK2<, Cyclin A1 is a protein that in humans is encoded by the CCNA1 gene, a href=, and CDC2 kinases, php?search_txt=cdk2> |
| Immunogen: |
Human recombinant CCNA1 protein (AA 64-263) was used as the immunogen for this Cyclin A antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cyclin A antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cyclin A (CCNA1) |
| Short name: |
Cyclin A Antibody (CCNA1) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cyclin A (Antibody to) (CCNA1) |
| Alternative technique: |
antibodies |
| Identity: |
1577 |
| Gene: |
CCNA1 |
More about : CCNA1 |
| Long gene name: |
cyclin A1 |
| Synonyms: |
CT146 |
| Locus: |
13q13, 3 |
| Discovery year: |
1999-01-06 |
| GenBank acession: |
U66838 |
| Entrez gene record: |
8900 |
| Pubmed identfication: |
9041194 |
| RefSeq identity: |
NM_003914 |
| Classification: |
Cyclins |
| Havana BLAST/BLAT: |
OTTHUMG00000016733 |