| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Cyclin A1 / CCNA1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
1-0, 5ug/ml, Western blot: 0 |
| Notes: |
Optimal dilution of the Cyclin A1 antibody should be determined by the researcher |
| Intented use: |
This Cyclin A1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P78396 |
| Purity: |
Antigen affinity |
| Description: |
Also this cyclin was found to bind to important cell cycle regulators, Cyclins function as regulators of CDK kinases, Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event, Multiple transcript variants encoding different isoforms have been found for this gene, The cyclin encoded by this gene was shown to be expressed in testis and brain, The protein encoded by this gene belongs to the highly conserved cyclin family, This cyclin binds both CDK2 and CDC2 kinases, and is thought to primarily function in the control of the germline meiotic cell cycle, and the p21 family proteins, and thus regulate separate functions in cell cycle, as well as in several leukemic cell lines, one appearing in S phase, such as Rb family proteins, the other in G2, transcription factor E2F-1, which give two distinct kinase activities, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle, Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene |
| Immunogen: |
Amino acids 64-263 of human Cyclin A1 were used as the immunogen for the Cyclin A1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Cyclin A1 antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Cyclin A1 / CCNA1 |
| Short name: |
Cyclin A1 Antibody / CCNA1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Cyclin A1 (Antibody to) / CCNA1 |
| Alternative technique: |
antibodies |
| Identity: |
1577 |
| Gene: |
CCNA1 |
More about : CCNA1 |
| Long gene name: |
cyclin A1 |
| Synonyms: |
CT146 |
| Locus: |
13q13, 3 |
| Discovery year: |
1999-01-06 |
| GenBank acession: |
U66838 |
| Entrez gene record: |
8900 |
| Pubmed identfication: |
9041194 |
| RefSeq identity: |
NM_003914 |
| Classification: |
Cyclins |
| Havana BLAST/BLAT: |
OTTHUMG00000016733 |