| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Optineurin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Optineurin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Optineurin antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
10133 |
| Purity: |
Antigen affinity |
| Description: |
<, Alternative splicing results in multiple transcript variants encoding the same protein, FIP2 or HYPL, It may also function in cellular morphogenesis and membrane trafficking, Optineurin interacts with adenovirus E3-14, This gene encodes the coiled-coil containing protein Optineurin which may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma, and transcription activation through its interactions with the <, and transcription factor IIIA proteins, inflammation or vasoconstriction, or <, pathways to mediate apoptosis, vesicle trafficking, /a>, /a>, /a>, /a>, /search_result, /search_result, /search_result, /search_result, 7K protein and may utilize <, Fas-ligand<, Huntingtin<, OPTN is also known as NRP, RAB8<, a href=, a href=, a href=, a href=, php?search_txt=TNFa>, php?search_txt=fas ligand>, php?search_txt=huntingtin>, php?search_txt=rab8>, tumor necrosis factor-alpha< |
| Immunogen: |
Human partial recombinant protein (AA 241-577) was used as the immunogen for this Optineurin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Optineurin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Optineurin |
| Short name: |
Optineurin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Optineurin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17142 |
| Gene: |
OPTN |
More about : OPTN |
| Long gene name: |
optineurin |
| Synonyms gene: |
GLC1E |
| Synonyms gene name: |
E (adult-onset) , glaucoma 1, open angle |
| Synonyms: |
FIP2 HYPL FIP-2 TFIIIA-INTP NRP HIP7 |
| Locus: |
10p13 |
| Discovery year: |
2001-11-16 |
| GenBank acession: |
AF420371 |
| Entrez gene record: |
10133 |
| Pubmed identfication: |
11834836 9488477 |
| RefSeq identity: |
NM_021980 |
| Havana BLAST/BLAT: |
OTTHUMG00000017690 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |