| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HEXB |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the HEXB antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This HEXB antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
3074 |
| Purity: |
Antigen affinity |
| Description: |
Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II), HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity, It is mapped to 5q13, and other molecules containing terminal N-acetyl hexosamines, catalyzes the degradation of the ganglioside GM2, together with the cofactor GM2 activator protein, 3, Hexosaminidase beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene |
| Immunogen: |
Human partial recombinant protein (AA 381-556) was used as the immunogen for this HEXB antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HEXB antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HEXB |
| Short name: |
HEXB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HEXB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4879 |
| Gene: |
HEXB |
More about : HEXB |
| Long gene name: |
hexosaminidase subunit beta |
| Synonyms gene name: |
hexosaminidase B (beta polypeptide) |
| Synonyms name: |
beta-hexosaminidase subunit beta |
| Locus: |
5q13, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M13519 |
| Entrez gene record: |
3074 |
| Pubmed identfication: |
2579389 3013851 |
| RefSeq identity: |
NM_000521 |
| Havana BLAST/BLAT: |
OTTHUMG00000102057 |
| Locus Specific Databases: |
HEXB Locus Database |