| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Furin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the Furin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This Furin antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
5045 |
| Purity: |
Antigen affinity |
| Description: |
Expression in T-cells is required for maintenance of peripheral immune tolerance, Furin is enriched in the Golgi apparatus, Furin is thought to play a role in tumor progression, It is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly, The gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26, The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family, also known as PACE, is a protein that in humans is encoded by the FURIN gene, where it functions to cleave other proteins into their mature/active forms, Furin (Fur) |
| Immunogen: |
Human partial recombinant protein (AA 591-794) was used as the immunogen for this Furin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Furin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Furin |
| Short name: |
Furin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
furin (paired basic amino acid cleaving enzyme) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8745 |
| Gene: |
PCSK3 |
More about : PCSK3 |
| Long gene name: |
furin, paired basic amino acid cleaving enzyme |
| Synonyms gene: |
FUR PACE |
| Synonyms gene name: |
membrane associated receptor protein) furin (paired basic amino acid cleaving enzyme) , paired basic amino acid cleaving enzyme (furin |
| Synonyms: |
SPC1 FURIN |
| Locus: |
15q26, 1 |
| Discovery year: |
1991-08-08 |
| GenBank acession: |
X17094 |
| Entrez gene record: |
5045 |
| Pubmed identfication: |
2251280 1741956 |
| RefSeq identity: |
NM_002569 |
| Classification: |
Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT: |
OTTHUMG00000149831 |