| Category: |
Antibody |
| Concentration: |
pH7, with 0, 02% sodium azide, 3, 5 mg/ml in 1X TBS, 5% BSA (US sourced) and 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
FURIN |
| Host animal: |
Goat (Capra aegagrus hircus) |
| Clonality: |
Polyclonal (goat origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA (peptide), WB (transfected) |
| Recommended dilutions: |
ELISA (peptide) LOD: 1:8000, Western blot: 1-3ug/ml |
| Notes: |
Optimal dilution of the FURIN antibody should be determined by the researcher |
| Intented use: |
This FURIN antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
5045 |
| Purity: |
Antigen affinity |
| Description: |
PACE, PCSK3, SPC1, Additional name(s) for this target protein: FUR |
| Immunogen: |
Amino acids RTKRDVYQEPTDP were used as the immunogen for this Furin antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot and store the FURIN antibody at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
FURIN |
| Short name: |
FURIN Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
furin (paired basic amino acid cleaving enzyme) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, FUR and PACE and PCSK3 and SPC1, FURIN and IDBG-30430 and ENSG00000140564 and 5045, FURIN and IDBG-629479 and ENSBTAG00000002939 and 281374, Furin and IDBG-195335 and ENSMUSG00000030530 and 18550, nerve growth factor binding, this GO :0000139 and this GO lgi membrane and cellular component this GO :0002020 and protease binding and molecular function this GO :0004175 and endopeptidase activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0004867 and serine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005796 and this GO lgi lumen and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006465 and signal peptide processing and biological process this GO :0006508 and proteolysis and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008233 and peptidase activity and molecular function this GO :0008283 and cell proliferation and biological process this GO :0009966 and regulation of signal transduction and biological process this GO :0009986 and cell surface and cellular component this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0016485 and protein processing and biological process this GO :0016486 and peptide hormone processing and biological process this GO :0017187 and peptidyl-glutamic acid carboxylation and biological process this GO :0019058 and viral life cycle and biological process this GO :0019068 and virion assembly and biological process this GO :0019082 and viral protein processing and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030140 and trans- this GO lgi network transport vesicle and cellular component this GO :0030198 and extracellular matrix organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0032455 and nerve growth factor processing and biological process this GO :0032804 and negative regulation of low-density lipoprotein particle receptor catabolic process and biological process this GO :0032902 and nerve growth factor production and biological process this GO :0032911 and negative regulation of transforming growth factor beta1 production and biological process this GO :0032940 and secretion by cell and biological process this GO :0042176 and regulation of protein catabolic process and biological process this GO :0042277 and peptide binding and molecular function this GO :0043043 and peptide biosynthetic process and biological process this GO :0043687 and post-translational protein modification and biological process this GO :0044267 and cellular protein metabolic process and biological process this GO :0045121 and membrane raft and cellular component this GO :0046872 and metal ion binding and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048406 and nerve growth factor binding and molecular function this GO :0051044 and positive regulation of membrane protein ectodomain proteolysis and biological process this GO :0052548 and regulation of endopeptidase activity and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0002020 : protease binding, this GO :0002020 : protease binding and also this GO :0004175 : endopeptidase activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0004867 : serine-type endopeptidase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0008233 : peptidase activity and also this GO :0042277 : peptide binding and also this GO :0046872 : metal ion binding and also this GO :0048406 : nerve growth factor binding, this GO :0004175 : endopeptidase activity, this GO :0004252 : serine-type endopeptidase activity, this GO :0004867 : serine-type endopeptidase inhibitor activity, this GO :0005515 : protein binding, this GO :0008233 : peptidase activity, this GO :0042277 : peptide binding, this GO :0046872 : metal ion binding, this GO :0048406 : nerve growth factor binding, furin (paired basic amino acid cleaving enzyme) |
| Identity: |
8568 |
| Gene: |
FURIN |
More about : FURIN |
| Long gene name: |
furin, paired basic amino acid cleaving enzyme |
| Synonyms gene: |
PCSK3 FUR PACE |
| Synonyms gene name: |
membrane associated receptor protein) furin (paired basic amino acid cleaving enzyme) , paired basic amino acid cleaving enzyme (furin |
| Synonyms: |
SPC1 |
| Locus: |
15q26, 1 |
| Discovery year: |
1991-08-08 |
| GenBank acession: |
X17094 |
| Entrez gene record: |
5045 |
| Pubmed identfication: |
2251280 1741956 |
| RefSeq identity: |
NM_002569 |
| Classification: |
Proprotein convertase subtilisin/kexin family |
| Havana BLAST/BLAT: |
OTTHUMG00000149831 |