| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TRPM2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the TRPM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TRPM2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O94759 |
| Purity: |
Antigen affinity |
| Description: |
Several alternatively spliced transcript variants of this gene have been described, TRPM2 is activated by oxidative stress and confers susceptibility to cell death, The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose, Using a cosmid/BAC contig, but their full-length nature is not known, this gene is mapped to chromosome 21q22, 3, Transient receptor potential cation channel subfamily M member 2 is a protein that in humans is encoded by the TRPM2 gene |
| Immunogen: |
An amino acid sequence from the N-terminus of human TRPM2 (CGYTHEQHLEEATKPH) was used as the immunogen for this TRPM2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TRPM2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TRPM2 |
| Short name: |
TRPM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRPM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12339 |
| Gene: |
TRPM2 |
More about : TRPM2 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 2 |
| Synonyms gene: |
TRPC7 |
| Synonyms gene name: |
member 2 , subfamily M, transient receptor potential cation channel |
| Synonyms: |
KNP3 LTRPC2 NUDT9L1 NUDT9H EREG1 |
| Locus: |
21q22, 3 |
| Discovery year: |
1998-03-23 |
| GenBank acession: |
AB001535 |
| Entrez gene record: |
7226 |
| Pubmed identfication: |
9806837 11385575 16382100 |
| RefSeq identity: |
NM_003307 |
| Classification: |
Nudix hydrolase family Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000040840 |