| Long name: |
TRPM2 Primary Polyclonal Antibody |
| Also known as: |
TRPM2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TRPM2 |
| Specificity: |
This is a highly specific antibody against TRPM2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
958-1008/1503 |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TRPM2 |
| Gene ID number: |
7226 |
| Swiss Prot: |
O94759 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activated by ADP-ribose, Confers susceptibility to cell death following oxidative stress, Extracellular calcium passes through the channel and acts from the intracellular side as a positive regulator in channel activation, Has ADP-ribose pyrophosphatase activity, Inactivated by intracellular ATP, Isoform 2 does not seem to be regulated by ADPR, nicotinamide adenine dinucleotide (NAD(+)), reactive nitrogen species and arachidonic acid, voltage-independent cation channel mediating sodium and calcium ion influx in response to oxidative stress, Nonselective |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
EREG1, Estrogen-responsive element-associated gene 1 protein, LTRPC2, LTrpC-2, Long transient receptor potential channel 2, NUDT9H, NUDT9L1, TRPC7, TRPM2, Transient receptor potential cation channel subfamily M member 2, Transient receptor potential channel 7, KNP3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TRPM2 |
| Short name: |
TRPM2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TRPM2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12339 |
| Gene: |
TRPM2 |
More about : TRPM2 |
| Long gene name: |
transient receptor potential cation channel subfamily M member 2 |
| Synonyms gene: |
TRPC7 |
| Synonyms gene name: |
member 2 , subfamily M, transient receptor potential cation channel |
| Synonyms: |
KNP3 LTRPC2 NUDT9L1 NUDT9H EREG1 |
| Locus: |
21q22, 3 |
| Discovery year: |
1998-03-23 |
| GenBank acession: |
AB001535 |
| Entrez gene record: |
7226 |
| Pubmed identfication: |
9806837 11385575 16382100 |
| RefSeq identity: |
NM_003307 |
| Classification: |
Nudix hydrolase family Transient receptor potential cation channels |
| Havana BLAST/BLAT: |
OTTHUMG00000040840 |