| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SLC12A6 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the SLC12A6 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SLC12A6 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UHW9 |
| Purity: |
Antigen affinity |
| Description: |
By radiation hybrid and somatic cell hybrid analyses, K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential, Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy, The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions, This gene is a member of the K-Cl cotransporter(KCC) family, also called KCC3, is a protein that in humans is encoded by the SLC12A6 gene, this gene is mapped to 15q14, Solute carrier family 12 (potassium/chloride transporters) member 6 |
| Immunogen: |
An amino acid sequence from the C-terminus of human SLC12A6 (QKAKSMEGFQDLLNMRPDQSN) was used as the immunogen for this SLC12A6 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SLC12A6 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SLC12A6 |
| Short name: |
SLC12A6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SLC12A6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10914 |
| Gene: |
SLC12A6 |
More about : SLC12A6 |
| Long gene name: |
solute carrier family 12 member 6 |
| Synonyms gene: |
KCC3 ACCPN |
| Synonyms gene name: |
agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome) solute carrier family 12 (potassium/chloride transporter), member 6 |
| Locus: |
15q14 |
| Discovery year: |
1999-05-25 |
| GenBank acession: |
AF108831 |
| Entrez gene record: |
9990 |
| Pubmed identfication: |
10187864 10347194 |
| RefSeq identity: |
NM_005135 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000129441 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_270 |