| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TrkB |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TrkB antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TrkB antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q16620 |
| Purity: |
Antigen affinity |
| Description: |
Alternate transcriptional splice variants encoding different isoforms have been found for this gene, Mutations in this gene have been associated with obesity and mood disorders, Signalling through this kinase leads to cell differentiation, This gene is mapped to 9q21, This kinase is a membrane-bound receptor that, TrkB is part of the large family of receptor tyrosine kinases, also known as BDNF/NT-3 growth factors receptor, is a protein that in humans is encoded by the NTRK2 gene, phosphorylates itself and members of the MAPK pathway, upon neurotrophin binding, 33, Neurotrophic tyrosine kinase receptor type 2 |
| Immunogen: |
An amino acid sequence from the N-terminus of human TrkB (EIFIANQKRLEIINEDDVEAY) was used as the immunogen for this TrkB antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TrkB antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TrkB |
| Short name: |
TrkB Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TrkB (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8032 |
| Gene: |
NTRK2 |
More about : NTRK2 |
| Long gene name: |
neurotrophic receptor tyrosine kinase 2 |
| Synonyms gene name: |
neurotrophic tyrosine kinase, receptor, type 2 |
| Synonyms: |
TRKB |
| Locus: |
9q21, 33 |
| Discovery year: |
1991-07-18 |
| GenBank acession: |
AF410902 |
| Entrez gene record: |
4915 |
| Pubmed identfication: |
7789988 |
| Classification: |
I-set domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000020120 |