| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RUNX3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Rat , we cannot guarantee that no other cross reactivity can occur, Mouse (Mus musculus) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the RUNX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This RUNX3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q64131 |
| Purity: |
Antigen affinity |
| Description: |
By fluorescence in situ hybridization, It may be involved in the control of cellular proliferation and/or differentiation, RUNX3 binds to the core site of murine Leukemia virus, RUNX3 was assigned to human chromosome 1p36, The RUNX3 gene encodes a Runt-related transcription factor, also called AML2 is a protein that in humans is encoded by the RUNX3 gene, and also to the enhancers of the T-cell receptor genes, the core sequences in the enhancer of the polyomavirus, which is part of the RUNX gene family, 11, Runt-related transcription factor 3 |
| Immunogen: |
An amino acid sequence from the middle region of mouse RUNX3 (QKIEDQTKAFPDRFGDLRMR) was used as the immunogen for this RUNX3 antibody (100% rat homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RUNX3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RUNX3 |
| Short name: |
RUNX3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
runt-related transcription factor 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AML2 and CBFA3 and PEBP2aC, ATP binding, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0007411 and axon guidance and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031175 and neuron projection development and biological process this GO :0032609 and interferon-gamma production and biological process this GO :0045087 and innate immune response and biological process this GO :0045786 and negative regulation of cell cycle and biological process this GO :0048469 and cell maturation and biological process this GO :0048935 and peripheral nervous system neuron development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, RUNX3 and IDBG-645327 and ENSBTAG00000019800 and 617389, RUNX3 and IDBG-94257 and ENSG00000020633 and 864, Runx3 and IDBG-196773 and ENSMUSG00000070691 and 12399, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000790 and nuclear chromatin and cellular component this GO :0000977 and RNA polymerase II regulatory region sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0002062 and chondrocyte differentiation and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006355 and regulation of transcription, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding, this GO :0000977 : RNA polymerase II regulatory region sequence-specific DNA binding and also this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding, this GO :0000981 : sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0003677 : DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, runt-related transcription factor 3 |
| Identity: |
10473 |
| Gene: |
RUNX3 |
More about : RUNX3 |
| Long gene name: |
runt related transcription factor 3 |
| Synonyms gene: |
CBFA3 |
| Synonyms gene name: |
runt-related transcription factor 3 |
| Synonyms: |
AML2 PEBP2A3 |
| Locus: |
1p36, 11 |
| Discovery year: |
1994-11-02 |
| GenBank acession: |
BC013362 |
| Entrez gene record: |
864 |
| Pubmed identfication: |
7835892 |
| RefSeq identity: |
NM_004350 |
| Havana BLAST/BLAT: |
OTTHUMG00000003316 |