| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
EPOR |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the EPOR antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This EPOR antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P19235 |
| Purity: |
Antigen affinity |
| Description: |
Akashi et al, Becker et al, Budarf et al, Jones et al, The distinction between the common lymphoid progenitor and common myeloid progenitor is that the common lymphoid progenitor expresses IL7R and does not express MPL, also called EPO Receptor, and characterization, is a protein that in humans is encoded by the EPOR gene, of a complementary clonogenic common myeloid progenitor that gives rise to all myeloid lineages, purification, using cell surface markers and flow cytometry, whereas the common myeloid progenitor does not express the IL7R and expresses MPL, (1990) isolated the human homolog of the murine erythropoietin receptor from an erythroleukemia cell line and from fetal liver, (1990) mapped the gene to human 19pter-q12 by somatic cell hybrid analysis, (2000) reported the prospective identification, (2010) showed by mathematical modeling of quantitative data and experimental validation that rapid ligand depletion and replenishment of the cell surface receptor are characteristic features of EPOR, Erythropoietin Receptor |
| Immunogen: |
An amino acid sequence from the middle region of human EPO Receptor (EHAQDTYLVLDKWLLPRN) was used as the immunogen for this EPOR antibody (100% mouse homology) |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the EPOR antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
EPOR |
| Short name: |
EPOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
erythropoietin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EPO-R, EPOR and IDBG-29281 and ENSG00000187266 and 2057, EPOR and IDBG-643528 and ENSBTAG00000008197 and 281144, Epor and IDBG-142378 and ENSMUSG00000006235 and 13857, Extracellular, identical protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004900 and erythropoietin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0038162 and erythropoietin-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046697 and decidualization and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004900 : erythropoietin receptor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0004900 : erythropoietin receptor activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, erythropoietin receptor |
| Identity: |
3829 |
| Gene: |
FRA10A |
More about : FRA10A |
| Long gene name: |
folic acid type, fra(10)(q23, fragile site, rare, 2) , 3) or fra(10)(q24 |
| Locus: |
10q23, 2 , 3 or 10q24 |
| Discovery year: |
1986-01-01 |
| Pubmed identfication: |
15203205 |