| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
ABCG2 (BCRP) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the ABCG2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This ABCG2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q9UNQ0 |
| Purity: |
Antigen affinity |
| Description: |
BCRP or MRX, In vitro assays of isolated membrane preparations revealed a high-capacity, Ozvegy et al, The ABCG2 gene is mapped on 4q22, Thegene encodes a membrane transporter belonging to the ATP-binding cassette(ABC) superfamily of membrane transporters, also known as ABCP, and dietary toxins to the milk of mice, and gut, and humans, carcinogens, cows, liver, member 2, subfamily g, vanadate-sensitive ATPase activity associated withABCG2expression that was stimulated by compounds known to be transported by this protein, which are involved in the trafficking of biologic molecules across cell membranes, which occurs in various plant-derived foods and food supplements and is highly efficient in limiting its uptake from ingested food, (2001)concluded thatthe proteinis likely functioning as a homodimer or homooligomer in this expression system since it is unlikely that putative Sf9 transport partners would be overexpressed at similarly high levels, 1, ABCG2is a major factor in the concentrative transfer of drugs, ATP-binding cassette, Abcg2transports pheophorbide-a, Theprotein is also a high capacity transporter for uric acid excretion in the kidney, is aprotein that in humans is encoded by the ABCG2gene |
| Immunogen: |
An amino acid sequence from the middle region of human BCRP/ABCG2 (NHEKNERINRVIQEL) was used as the immunogen for this ABCG2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the ABCG2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
ABCG2 (BCRP) |
| Short name: |
ABCG2 Antibody (BCRP) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ABCG2 (Antibody to) (BCRP) |
| Alternative technique: |
antibodies |
| Identity: |
74 |
| Gene: |
ABCG2 |
More about : ABCG2 |
| Long gene name: |
ATP binding cassette subfamily G member 2 (Junior blood group) |
| Synonyms gene name: |
ATP-binding cassette, member 2 (Junior blood group) , member 2 ATP-binding cassette, sub-family G (WHITE), sub-family G (WHITE) |
| Synonyms: |
EST157481 MXR BCRP ABCP CD338 |
| Locus: |
4q22, 1 |
| Discovery year: |
1999-10-26 |
| GenBank acession: |
AF103796 |
| Entrez gene record: |
9429 |
| Pubmed identfication: |
8894702 9861027 |
| RefSeq identity: |
NM_004827 |
| Classification: |
CD molecules Blood group antigens ATP binding cassette subfamily G |
| Havana BLAST/BLAT: |
OTTHUMG00000130601 |
| Locus Specific Databases: |
LRG_823 |