| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
RIP2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the RIP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This RIP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O43353 |
| Purity: |
Antigen affinity |
| Description: |
CARDIAK, CARDIAK (CARD-containing ICE-associated kinase) specifically interacted with the CARD of ICE/caspase-1, It has 540-amino acid protein in length, It is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway, It is a potent activator of NF-kappa Band inducer of apoptosis in response to various stimuli, Northern blot analysis revealed that RIPK2 is expressed in various human tissues as 2, RICK, The encoded protein contains a C-terminalcaspase recruitment domain(CARD), This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, also known as CARD3, and RIP2, and is a component of signaling complexes in both the innate and adaptive immune pathways, and this interaction correlated with the processing of pro-caspase-1 and the formation of the active caspase-1 p20 subunit, is an enzyme that in humans is encoded by the RIPK2 gene, 5- and 1, 8-kb mRNAs that differ due to alternative polyadenylation, Receptor-interacting serine/threonine-protein kinase 2 |
| Immunogen: |
An amino acid sequence from the C-terminus of human RIP2 (DIQGEEFAKVIVQKLKDNKQ) was used as the immunogen for this RIP2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the RIP2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
RIP2 |
| Short name: |
RIP2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
RIP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30322 |
| Gene: |
ARHGEF28 |
More about : ARHGEF28 |
| Long gene name: |
Rho guanine nucleotide exchange factor 28 |
| Synonyms gene name: |
Rho guanine nucleotide exchange factor (GEF) 28 |
| Synonyms: |
RGNEF p190RhoGEF RIP2 |
| Locus: |
5q13, 2 |
| Discovery year: |
2012-08-08 |
| Entrez gene record: |
64283 |
| Pubmed identfication: |
9199174 11058585 |
| Havana BLAST/BLAT: |
OTTHUMG00000162454 |