| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SERT (Serotonin transporter) |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the SERT antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SERT antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P31645 |
| Purity: |
Antigen affinity |
| Description: |
A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, It is a member of the sodium:neurotransmitter symporter family, The SLC6A4 gene spans 31 kb and contains 14 exons, This protein integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons, This protein is the target of many antidepressant medications, This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner, aggressive behavior in Alzheimer disease patients, also known as SERT (Serotonin transporter), including those of the SSRI class, is a monoamine transporter protein, member 4), post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma, SLC6A4 (Solute carrier family 6 |
| Immunogen: |
An amino acid sequence from the N-terminus of human Serotonin transporter (NSQKVLSECKDREDCQEN) was used as the immunogen for this SERT antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SERT antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SERT (Serotonin transporter) |
| Short name: |
SERT Antibody (Serotonin transporter) |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SERT (Antibody to) (Serotonin transporter) |
| Alternative technique: |
antibodies |