| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SSTR2 Somatostatin Receptor 2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the SSTR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SSTR2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P30874 |
| Purity: |
Antigen affinity |
| Description: |
SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney, Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins, Stable transfection of human pancreatic cells, The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner, These effects occur as a consequence of an autocrine SSTR2-dependent loop, and metastasis, inhibits cell proliferation, mRNA was variably expressed in all neuroblastoma tumors with a relevant reduction in the more advanced stage, somatostatin, tumorigenicity, whereby SSTR2 induces expression of its own ligand, which do not endogenously express SSTR2, Somatostatin receptor type 2 is a protein that in humans is encoded by the SSTR2 gene |
| Immunogen: |
mouse and rat), An amino acid sequence from the middle region of human Somatostatin Receptor 2 (RSNQWGRSSCTINWP) was used as the immunogen for this SSTR2 antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SSTR2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SSTR2 Somatostatin Receptor 2 |
| Short name: |
SSTR2 Antibody Somatostatin Receptor 2 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SSTR2 (Antibody to) Somatostatin Receptor 2 |
| Alternative technique: |
antibodies |
| Identity: |
11331 |
| Gene: |
SSTR2 |
More about : SSTR2 |
| Long gene name: |
somatostatin receptor 2 |
| Locus: |
17q25, 1 |
| Discovery year: |
1992-08-25 |
| Entrez gene record: |
6752 |
| Pubmed identfication: |
8449518 |
| Classification: |
Somatostatin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000178343 |