| Long name: |
SSTR2/Somatostatin Receptor 2 Antibody |
| Also known as: |
SSTR2/Somatostatin Receptor 2 Antibody |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SSTR2/Somatostatin Receptor 2 |
| Specificity: |
This is a highly specific antibody against SSTR2/Somatostatin Receptor 2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
230-253/369 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SSTR2 |
| Gene ID number: |
6752 |
| Swiss Prot: |
P30874 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion, In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins, Inactivates SSTR3 receptor function following heterodimerization, Inhibits calcium entry by suppressing voltage-dependent calcium channels, Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B, Mediates negative regulation of insulin receptor signaling through PTPN6, Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development, This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase, Receptor for somatostatin-14 and -28 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
SRIF-1, SS-2-R, SS2-R, SS2R, SSTR2, Somatostatin receptor type 2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SSTR2/Somatostatin Receptor 2 |
| Short name: |
SSTR2/Somatostatin Receptor 2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SSTR2/Somatostatin Receptor 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11331 |
| Gene: |
SSTR2 |
More about : SSTR2 |
| Long gene name: |
somatostatin receptor 2 |
| Locus: |
17q25, 1 |
| Discovery year: |
1992-08-25 |
| Entrez gene record: |
6752 |
| Pubmed identfication: |
8449518 |
| Classification: |
Somatostatin receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000178343 |