| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SLC10A1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the SLC10A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use: |
This SLC10A1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q14973 |
| Purity: |
Antigen affinity |
| Description: |
Injection of in vitro transcribed NTCP cRNA into Xenopus oocytes resulted in the expression of Na(+)-dependent taurocholate uptake, Like other sodium/bile acid transporters, NTCP-mediated taurocholate uptake in oocytes was inhibited by all major bile acid derivatives and by bromosulfophthalein, SLC10A1 contains an exoplasmic N terminus, The SLC10A1 gene is mapped on 14q24, Two amphipathic sequences are critical for intramolecular interactions and for proper trafficking of SLC10A1 to the plasma membrane, also called NTCP or NTCP1, an odd number of transmembrane regions, and a cytoplasmic C terminus, is found in the basolateral membranes of hepatocytes, member 1), which is also involved in the reabsorption of bile acids, 2 and contains 5 exons and spans about 23 kb, SLC10A1 (Solute carrier family 10 (sodium/bile acid cotransporter family) |
| Immunogen: |
Amino acids 141-154 (YSRGIYDGDLKDKV-human) were used as the immunogen for this SLC10A1 antibody |
| Storage: |
After reconstitution, Avoid repeated freezing and thawing, Celcius or lower, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, The lyophilized SLC10A1 antibody can be stored at 4oC to -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SLC10A1 |
| Short name: |
SLC10A1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SLC10A1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10905 |
| Gene: |
SLC10A1 |
More about : SLC10A1 |
| Long gene name: |
solute carrier family 10 member 1 |
| Synonyms gene name: |
member 1 , solute carrier family 10 (sodium/bile acid cotransporter) |
| Synonyms: |
NTCP |
| Synonyms name: |
Na+/taurocholate cotransporting polypeptide |
| Locus: |
14q24, 1 |
| Discovery year: |
1994-02-16 |
| GenBank acession: |
L21893 |
| Entrez gene record: |
6554 |
| Pubmed identfication: |
8132774 |
| Classification: |
Solute carriers |
| Havana BLAST/BLAT: |
OTTHUMG00000171236 |