| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
CXCL4 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the CXCL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This CXCL4 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P02776 |
| Purity: |
Antigen affinity |
| Description: |
As a strong chemoattractant for neutrophils and fibroblasts, By in situ hybridization, CXCL4s major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, It belongs to the CXC chemokine family, It is encoded on a 10-kb EcoRI fragment of genomic DNA, The gene contains 3 exons spanning approximately 1 kb, is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin, the cytokine probably has a role in inflammation and wound repair, the gene is mapped to chromosome 4q12-q21, thereby inhibiting local antithrombin III activity and promoting coagulation, Chemokine (C-X-C motif) ligand 4 |
| Immunogen: |
Amino acids 85-101 (DLQAPLYKKIIKKLLES-human) were used as the immunogen for this CXCL4 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the CXCL4 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
CXCL4 |
| Short name: |
CXCL4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
CXCL4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
8861 |
| Gene: |
PF4 |
More about : PF4 |
| Long gene name: |
platelet factor 4 |
| Synonyms gene name: |
platelet factor 4 |
| Synonyms: |
SCYB4 CXCL4 |
| Synonyms name: |
chemokine (C-X-C motif) ligand 4 |
| Locus: |
4q13, 3 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M25897 |
| Entrez gene record: |
5196 |
| Pubmed identfication: |
3622011 |
| Havana BLAST/BLAT: |
OTTHUMG00000130009 |