| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
HSP90 alpha / HSP90AA1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the HSP90 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This HSP90 alpha antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P07900 |
| Purity: |
Antigen affinity |
| Description: |
Cytoplasmic HSP90 is essential for viability under all conditions in eukaryotes, HSP90 is found in bacteria and all branches of eukarya, It is a member of the heat shock protein family which is upregulated in response to stress, Researchers later realized that HSP90 has other essential functions in unstressed cells, The function of Hsp90 includes assisting in protein folding, These cells were stressed by heating, This protein was first isolated by extracting proteins from stressed cells, all of which caused the cells proteins to begin to denature, and tumor repression, but it is apparently absent in archaea, cell signaling, dehydrating or by other means, the bacterial homologue HtpG is dispensable under non-heat stress conditions, Heat shock protein 90 is a molecular chaperone and is one of the most abundant proteins expressed in cells |
| Immunogen: |
mouse and rat), Amino acids 676-693 (FSLEDPQTHANRIYRMIK) from the alpha form were used as the immunogen for this HSP90 alpha antibody (100% homologous in human |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the HSP90 alpha antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
HSP90 alpha / HSP90AA1 |
| Short name: |
HSP90 alpha Antibody / HSP90AA1 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
HSP90 a (Antibody to) / HSP90AA1 |
| Alternative technique: |
antibodies |
| Identity: |
5253 |
| Gene: |
HSP90AA1 |
More about : HSP90AA1 |
| Long gene name: |
heat shock protein 90 alpha family class A member 1 |
| Synonyms gene: |
HSPC1 HSPCA |
| Synonyms gene name: |
alpha heat shock 90kDa protein 1, alpha heat shock protein 90kDa alpha (cytosolic), class A member 1 , heat shock 90kD protein 1 |
| Synonyms: |
Hsp89 Hsp90 FLJ31884 HSP90N |
| Locus: |
14q32, 31 |
| Discovery year: |
1990-06-27 |
| GenBank acession: |
M27024 |
| Entrez gene record: |
3320 |
| Pubmed identfication: |
2527334 16269234 |
| RefSeq identity: |
NM_005348 |
| Classification: |
Heat shock 90kDa proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000171752 |