| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
XAF1 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the XAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This XAF1 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
Q6GPH4 |
| Purity: |
Antigen affinity |
| Description: |
All members of this family possess baculoviral IAP(BIR) repeats, And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells, MIM 300079) is a potent member of the IAP family, X-linked inhibitor of apoptosis(XIAP, XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells, also known as XAF1, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases, is a human gene, XIAP associated factor-1 |
| Immunogen: |
An amino acid sequence from the C-terminus of human XAF1 (QEKCRWLASSKGKQVRNFS) was used as the immunogen for this XAF1 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the XAF1 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
XAF1 |
| Short name: |
XAF1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
X-linked inhibitor on apoptosis associated factor 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
XAF1 and IDBG-22619 and ENSG00000132530 and 54739, XAF1 and IDBG-633696 and ENSBTAG00000011343 and 509740, Xaf1 and IDBG-196515 and ENSMUSG00000040483 and 327959, nuclei, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005829 and cytosol and cellular component this GO :0006915 and apoptotic process and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0031333 and negative regulation of protein complex assembly and biological process this GO :0035456 and response to interferon-beta and biological process this GO :0060337 and type I interferon signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding, this GO :0008270 : zinc ion binding, zinc ion binding, XIAP associated factor 1 |
| Identity: |
30932 |
| Gene: |
XAF1 |
More about : XAF1 |
| Long gene name: |
XIAP associated factor 1 |
| Synonyms: |
BIRC4BP XIAPAF1 HSXIAPAF1 |
| Locus: |
17p13, 2 |
| Discovery year: |
2008-03-04 |
| GenBank acession: |
X99699 |
| Entrez gene record: |
54739 |
| Pubmed identfication: |
12029096 11175744 |
| RefSeq identity: |
NM_017523 |
| Havana BLAST/BLAT: |
OTTHUMG00000177908 |