| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
TIE2 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
5-1ug/ml, Western blot: 0 |
| Notes: |
Titration of the TIE2 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This TIE2 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
7010 |
| Purity: |
Antigen affinity |
| Description: |
HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche, Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP, The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, The ligand <, also known as TEK tyrosine kinase, binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development, is a receptor that belongs to the Tie2 family, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats, /a>, /search_result, Angiopoietin-1<, Tyrosine kinase with Ig and EGF homology domains 2, a href=, php?search_txt=ang1> |
| Immunogen: |
Human partial recombinant protein (AA 641-830) was used as the immunogen for this TIE2 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the TIE2 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
TIE2 |
| Short name: |
TIE2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TIE2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11724 |
| Gene: |
TEK |
More about : TEK |
| Long gene name: |
TEK receptor tyrosine kinase |
| Synonyms gene: |
VMCM |
| Synonyms gene name: |
endothelial , multiple cutaneous and mucosal TEK tyrosine kinase, venous malformations |
| Synonyms: |
TIE2 TIE-2 VMCM1 CD202b |
| Locus: |
9p21, 2 |
| Discovery year: |
1994-05-24 |
| GenBank acession: |
L06139 |
| Entrez gene record: |
7010 |
| Pubmed identfication: |
1312667 7833915 |
| Classification: |
Fibronectin type III domain containing CD molecules Immunoglobulin like domain containing Receptor Tyrosine Kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000019712 |