| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Survivin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ELISA, IHC-P, WB |
| Recommended dilutions: |
1-0, 5-1ug/ml, 5-1ug/ml, 5ug/ml, ELISA: 0, IHC (Paraffin): 0, Western blot: 0 |
| Notes: |
Titration of the Survivin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting points |
| Intented use: |
This Survivin antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
O15392 |
| Purity: |
Antigen affinity |
| Description: |
It is a member of the inhibitor of apoptosis (IAP) family, It is expressed highly in most human tumours and fetal tissue, The Survivin protein functions to inhibit caspase activation, The gene is mapped to chromosome 17q25 by pulsed field gel electrophoresis and single- and two-color FISH, also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5, but is completely absent in terminally differentiated cells, in humans, is a protein that, is encoded by the BIRC5 gene, thereby leading to negative regulation of apoptosis or programmed cell death, Survivin |
| Immunogen: |
Human partial recombinant protein (AA 1-142) was used as the immunogen for this Survivin antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Survivin antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Survivin |
| Short name: |
Survivin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Survivin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
593 |
| Gene: |
BIRC5 |
More about : BIRC5 |
| Long gene name: |
baculoviral IAP repeat containing 5 |
| Synonyms gene: |
API4 |
| Synonyms gene name: |
apoptosis inhibitor 4 baculoviral IAP repeat-containing 5 |
| Synonyms: |
EPR-1 survivin |
| Synonyms name: |
survivin variant 3 alpha |
| Locus: |
17q25, 3 |
| Discovery year: |
1998-06-10 |
| GenBank acession: |
U75285 |
| Entrez gene record: |
332 |
| Pubmed identfication: |
8106347 7947793 |
| RefSeq identity: |
NM_001168 |
| Classification: |
Baculoviral IAP repeat containing Chromosomal passenger complex |
| Havana BLAST/BLAT: |
OTTHUMG00000177505 |