| Category: |
Antibody |
| Concentration: |
05% sodium azide, 1 mg/ml BSA (US sourced) and 0, 5 mg/ml in 1X PBS with 0 |
| Form: |
Purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
Survivin |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
WB |
| Recommended dilutions: |
Western blot: 2-5ug/ml |
| Notes: |
antibody titration may be required for optimal results, Provided assay concentrations are suggestions only |
| Added buffer: |
pH 7, 1X Phosphate Buffered Saline (PBS), 4 |
| Intented use: |
This Survivin antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID #: |
332 |
| Purity: |
Purified by protein A Affinity Chromatography |
| Description: |
Expression is regulated by p53, It is a member of the IAP (inhibitor of apoptosis family, Survivin binds to the active form of Caspase-3 and -7, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level, also called BIRC5, effector or executioner caspases, is a protein encoded by the human BIRC5 gene, preventing them from continuing the apoptosis-signaling cascade, Survivin |
| Immunogen: |
A recombinant protein fragment from human Survivin was used as the immunogen for this antibody |
| Storage: |
Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the antibody and store frozen at -20 deg |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
Survivin |
| Short name: |
Survivin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Survivin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
593 |
| Gene: |
BIRC5 |
More about : BIRC5 |
| Long gene name: |
baculoviral IAP repeat containing 5 |
| Synonyms gene: |
API4 |
| Synonyms gene name: |
apoptosis inhibitor 4 baculoviral IAP repeat-containing 5 |
| Synonyms: |
EPR-1 survivin |
| Synonyms name: |
survivin variant 3 alpha |
| Locus: |
17q25, 3 |
| Discovery year: |
1998-06-10 |
| GenBank acession: |
U75285 |
| Entrez gene record: |
332 |
| Pubmed identfication: |
8106347 7947793 |
| RefSeq identity: |
NM_001168 |
| Classification: |
Baculoviral IAP repeat containing Chromosomal passenger complex |
| Havana BLAST/BLAT: |
OTTHUMG00000177505 |