| known also as: |
Anti-GOAT ANTI HUMAN SURVIVIN (C-TERMINAL) |
| known also as: |
Caprine ANTI HUMAN SURVIVIN (C-TERMINAL) |
| known also as: |
Caprinae ANTI Homo sapiens SURVIVIN (C-TERMINAL) |
| known also as: |
SURVIVIN |
| Other names: |
Apoptosis inhibitor 4, Apoptosis inhibitor survivin, Baculoviral IAP repeat-containing protein 5, apoptosis inhibitor 4, apoptosis inhibitor survivin, baculoviral IAP repeat containing 5, baculoviral IAP repeat-containing protein 5, survivin variant 3 alpha, baculoviral IAP repeat-containing protein 5 isoform 2 |
| Other gene names: |
API4, API4, BIRC5, EPR-1, IAP4, BIRC5 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Goat |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
The lack of survivin expression by normal non-malignant cells, _x000D__x000D_Survivin is only expressed during the G2-M cell cycle phase, a novel inhibitor of apoptosis (IAP) protein, and component of the chromosomal passenger complex, and in many human cancers, and is predominantly expressed in foetal tissues, including adenocarcinomas and high-grade lymphomas, makes survivin an important therapeutic target for cancer, otherwise known as TIAP/BIRC5, which plays a key role in the regulation of mitosis, SURVIVIN This item specifically recognises an epitope within the C-terminal (CT) region of human Survivin |
| Form/Appearance: |
Purified (Purified IgG - liquid) |
| Concentration: |
IgG concentration 500ug/1000ul |
| Storage and shipping: |
Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
SURVIVIN |
| Short name: |
GOAT ANTI HUMAN SURVIVIN (C-TERMINAL) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens SURVIVIN (C-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique: |
antibodies |
| Identity: |
593 |
| Gene: |
BIRC5 |
More about : BIRC5 |
| Long gene name: |
baculoviral IAP repeat containing 5 |
| Synonyms gene: |
API4 |
| Synonyms gene name: |
apoptosis inhibitor 4 baculoviral IAP repeat-containing 5 |
| Synonyms: |
EPR-1 survivin |
| Synonyms name: |
survivin variant 3 alpha |
| Locus: |
17q25, 3 |
| Discovery year: |
1998-06-10 |
| GenBank acession: |
U75285 |
| Entrez gene record: |
332 |
| Pubmed identfication: |
8106347 7947793 |
| RefSeq identity: |
NM_001168 |
| Classification: |
Baculoviral IAP repeat containing Chromosomal passenger complex |
| Havana BLAST/BLAT: |
OTTHUMG00000177505 |